Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SPN034183_RS07460 Genome accession   NC_021028
Coordinates   1399624..1400856 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae SPN034183     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1394624..1405856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN034183_RS07430 (SPN034183_13710) - 1394814..1395779 (+) 966 WP_000080993.1 NAD(P)/FAD-dependent oxidoreductase -
  SPN034183_RS07435 (SPN034183_13720) whiA 1395813..1396724 (-) 912 WP_000011276.1 DNA-binding protein WhiA -
  SPN034183_RS07440 (SPN034183_13730) - 1396721..1397698 (-) 978 WP_001231090.1 YvcK family protein -
  SPN034183_RS07445 (SPN034183_13740) rapZ 1397695..1398585 (-) 891 WP_000163033.1 RNase adapter RapZ -
  SPN034183_RS07450 (SPN034183_13750) - 1398637..1399017 (-) 381 WP_001140412.1 RidA family protein -
  SPN034183_RS07455 (SPN034183_13760) yihA 1399028..1399615 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SPN034183_RS07460 (SPN034183_13770) clpX 1399624..1400856 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SPN034183_RS12775 (SPN034183_13780) - 1400888..1401058 (-) 171 WP_000442275.1 hypothetical protein -
  SPN034183_RS07470 (SPN034183_13790) - 1401058..1401564 (-) 507 WP_015545705.1 dihydrofolate reductase -
  SPN034183_RS07475 (SPN034183_13800) - 1401694..1402213 (-) 520 Protein_1441 Dps family protein -
  SPN034183_RS07480 (SPN034183_13810) - 1402710..1404032 (-) 1323 Protein_1442 GH25 family lysozyme -
  SPN034183_RS07485 (SPN034183_13820) tpiA 1404070..1404828 (-) 759 WP_000087896.1 triose-phosphate isomerase -
  SPN034183_RS07490 (SPN034183_13830) - 1404925..1405602 (-) 678 WP_000221614.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=58180 SPN034183_RS07460 WP_000106346.1 1399624..1400856(-) (clpX) [Streptococcus pneumoniae SPN034183]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=58180 SPN034183_RS07460 WP_000106346.1 1399624..1400856(-) (clpX) [Streptococcus pneumoniae SPN034183]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTGGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATTGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment