Detailed information    

insolico Bioinformatically predicted

Overview


Name   pptA   Type   Regulator
Locus tag   SPN034183_RS02635 Genome accession   NC_021028
Coordinates   486323..487054 (+) Length   243 a.a.
NCBI ID   WP_000889923.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN034183     
Function   export ComS (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 485548..495092 486323..487054 within 0


Gene organization within MGE regions


Location: 485548..495092
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN034183_RS02625 (SPN034183_04830) - 485548..485835 (-) 288 WP_000777760.1 hypothetical protein -
  SPN034183_RS02630 (SPN034183_04840) - 485845..486255 (-) 411 WP_001278301.1 HIT family protein -
  SPN034183_RS02635 (SPN034183_04850) pptA 486323..487054 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  SPN034183_RS02640 (SPN034183_04860) - 487051..488100 (+) 1050 WP_000653752.1 ABC transporter permease -
  SPN034183_RS02645 (SPN034183_04870) - 488268..488597 (-) 330 WP_000132570.1 hypothetical protein -
  SPN034183_RS02650 (SPN034183_04880) - 488873..489211 (+) 339 WP_000682119.1 LytTR family DNA-binding domain-containing protein -
  SPN034183_RS02655 (SPN034183_04890) comE/blpR 489216..489953 (+) 738 WP_001219127.1 response regulator transcription factor Regulator
  SPN034183_RS02660 (SPN034183_04900) - 489967..491307 (+) 1341 WP_001017622.1 sensor histidine kinase -
  SPN034183_RS02665 (SPN034183_04910) blpC 491349..491504 (-) 156 WP_000358813.1 quorum-sensing system pheromone BlpC -
  SPN034183_RS02670 (SPN034183_04920) - 491561..492922 (-) 1362 WP_015545695.1 bacteriocin secretion accessory protein -
  SPN034183_RS13405 comA/nlmT 492933..493436 (-) 504 WP_001808910.1 ATP-binding cassette domain-containing protein Regulator
  SPN034183_RS13410 comA/nlmT 493405..493845 (-) 441 WP_001808911.1 ATP-binding cassette domain-containing protein Regulator
  SPN034183_RS13415 comA/nlmT 493835..494560 (-) 726 WP_167750760.1 ABC transporter transmembrane domain-containing protein Regulator
  SPN034183_RS13420 (SPN034183_04940) comA/nlmT 494505..495092 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator

Sequence


Protein


Download         Length: 243 a.a.        Molecular weight: 27026.52 Da        Isoelectric Point: 4.7792

>NTDB_id=58159 SPN034183_RS02635 WP_000889923.1 486323..487054(+) (pptA) [Streptococcus pneumoniae SPN034183]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL

Nucleotide


Download         Length: 732 bp        

>NTDB_id=58159 SPN034183_RS02635 WP_000889923.1 486323..487054(+) (pptA) [Streptococcus pneumoniae SPN034183]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTTCCTGTTTTGAAAGATGTGTCCTTTACTGTTGAAAGTGG
GCAGTTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCAACGACGATCAATGAGATTATCGGTCTGTTGGCACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACTCTGCAAGGAGATGCGACTAGCTACCGCAAGCAGATTGGCTACATTCCT
GAGACGCCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTACGGTATTGAGCAAAA
AGTGGCTTTCGAACGAGTAGAGCCCTTGTTAAAAATGTTCCGTTTGGAACAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTGGCTATTTCTGATTTGATTCAGCTTTTGGAAGTGGAGAAGCAAAAGGGCAAGTCTATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAAAAGATGTGTGATGCCTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCCAAAG
GCAATCTCCTGCAACTACGTGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACCAAAGAG
GAGGATCTATGA

Domains


Predicted by InterproScan.

(17-160)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.199

99.177

0.716

  pptA Streptococcus thermophilus LMD-9

71.369

99.177

0.708


Multiple sequence alignment