Detailed information NTG0581294

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: I6L88_RS02105
• Genome accession: NZ_CP077404
• Coordinates: 385461..386342 (+)
• Length: 293 a.a.
• NCBI ID: WP_002262935.1
• Uniprot ID: Q8DT59
• Organism: Streptococcus mutans strain FDAARGOS 1458
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 380461..391342

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6L88_RS02075 (I6L88_02075)	-	380646..381524 (+)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-
I6L88_RS02080 (I6L88_02080)	atpD	381550..382956 (+)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
I6L88_RS02085 (I6L88_02085)	-	382970..383386 (+)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
I6L88_RS02090 (I6L88_02090)	-	383658..383891 (+)	234	WP_002285829.1	DUF1146 family protein	-
I6L88_RS02095 (I6L88_02095)	murA	383957..385228 (+)	1272	WP_002262937.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
I6L88_RS02100 (I6L88_02100)	-	385231..385419 (+)	189	WP_002279970.1	DNA-directed RNA polymerase subunit beta	-
I6L88_RS02105 (I6L88_02105)	endA	385461..386342 (+)	882	WP_002262935.1	DNA/RNA non-specific endonuclease	Machinery gene
I6L88_RS02110 (I6L88_02110)	-	386410..387060 (-)	651	WP_002279971.1	amino acid ABC transporter permease	-
I6L88_RS02115 (I6L88_02115)	-	387075..387779 (-)	705	WP_002264823.1	amino acid ABC transporter permease	-
I6L88_RS02120 (I6L88_02120)	-	387797..388609 (-)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
I6L88_RS02125 (I6L88_02125)	-	388606..389388 (-)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
I6L88_RS02130 (I6L88_02130)	vicR	389741..390448 (+)	708	WP_002262930.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32130.72 Da
• Isoelectric Point: 9.5337

>NTDB_id=581294 I6L88_RS02105 WP_002262935.1 385461..386342(+) (endA) [Streptococcus mutans strain FDAARGOS 1458]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYASNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=581294 I6L88_RS02105 WP_002262935.1 385461..386342(+) (endA) [Streptococcus mutans strain FDAARGOS 1458]
ATGACTAGAAAAACGAACAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAGTAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-251)

3D structure

• AlphaFold DB: Q8DT59

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.103	79.863	0.512
endA	Streptococcus pneumoniae D39	64.103	79.863	0.512
endA	Streptococcus pneumoniae R6	64.103	79.863	0.512
endA	Streptococcus pneumoniae TIGR4	64.103	79.863	0.512