Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   I6L86_RS04850 Genome accession   NZ_CP077259
Coordinates   1033468..1034292 (+) Length   274 a.a.
NCBI ID   WP_023947085.1    Uniprot ID   A0A1X1L3P9
Organism   Streptococcus mitis strain FDAARGOS 1456     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1028468..1039292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L86_RS04815 (I6L86_04815) asnA 1028559..1029551 (+) 993 WP_000748003.1 aspartate--ammonia ligase -
  I6L86_RS04820 (I6L86_04820) rsmD 1029616..1030155 (+) 540 WP_004238805.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  I6L86_RS04825 (I6L86_04825) coaD 1030145..1030633 (+) 489 WP_001280765.1 pantetheine-phosphate adenylyltransferase -
  I6L86_RS04830 (I6L86_04830) sepM 1030617..1031654 (+) 1038 WP_000727271.1 SepM family pheromone-processing serine protease Regulator
  I6L86_RS04835 (I6L86_04835) - 1031711..1031941 (+) 231 WP_000250399.1 DUF1146 family protein -
  I6L86_RS04840 (I6L86_04840) murA 1031965..1033248 (+) 1284 WP_000411901.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  I6L86_RS04845 (I6L86_04845) - 1033241..1033429 (+) 189 WP_004241151.1 DNA-directed RNA polymerase subunit beta -
  I6L86_RS04850 (I6L86_04850) endA 1033468..1034292 (+) 825 WP_023947085.1 DNA-entry nuclease EndA Machinery gene
  I6L86_RS04855 (I6L86_04855) - 1034559..1035890 (+) 1332 WP_000390033.1 hemolysin family protein -
  I6L86_RS04865 (I6L86_04865) amiA3 1036321..1038309 (+) 1989 WP_000749582.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29924.56 Da        Isoelectric Point: 9.8622

>NTDB_id=580381 I6L86_RS04850 WP_023947085.1 1033468..1034292(+) (endA) [Streptococcus mitis strain FDAARGOS 1456]
MDKKTRQTLIGLLVLLLLSAGSYYIKQMQSTANSPKTKVSQKKQASEAPSQELAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESMVRKALDKNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=580381 I6L86_RS04850 WP_023947085.1 1033468..1034292(+) (endA) [Streptococcus mitis strain FDAARGOS 1456]
ATGGATAAAAAAACAAGACAGACACTGATCGGACTGCTAGTGTTATTGCTTTTATCTGCGGGAAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACAAAGGTTAGTCAGAAAAAACAAGCGTCGGAAGCTCCTAGTCAAGAATTGG
CAGAAAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAAGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGATAATAAAACAAAGACAGTGGGAAAGGA
AACAGTGCCAACCGTAGCAAATGCCCTCTTGTCTAAGGCTACTCGTCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CGACTTCATGGACTCCTCCAGGCTGGCATCAGGTTAAGAATCTAAAGGGTACTTATACCCATGCGGTCGATAGAGGTCAC
TTGTTAGGCTATGCCTTAATCGGTGGCTTGGATGGTTTTGATGCCTCGACAAGCAATCCTAAAAACATTGCTGTTCAAAC
AGCCTGGGCAAATCAGGCTCAAGCCGAGGATTCGACTGGTCAAAACTACTATGAAAGCATGGTACGTAAGGCCTTGGATA
AAAACAAGCGTGTTCGTTACCGTGTAACTCTTTATTATGCTTCAAACGAGGATTTAGTTCCTTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGACGGAGAATTGGAATTTAATGTTCTAGTTCCCAATGTTCAAAAAGGGCTTCAACTGGATTACCGAAC
TGGAGAAGTGACTGTTACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1L3P9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

95.255

100

0.953
  endA Streptococcus pneumoniae D39

95.255

100

0.953
  endA Streptococcus pneumoniae R6

95.255

100

0.953
  endA Streptococcus pneumoniae TIGR4

95.255

100

0.953