NTDB

Overview

Name	cinA	Type	Machinery gene
Locus tag	KPU60_RS02555	Genome accession	NZ_CP076488
Coordinates	496865..498109 (+)	Length	414 a.a.
NCBI ID	WP_002365395.1	Uniprot ID	A0A855UKS7
Organism	Enterococcus faecalis strain UAMS_EL56
Function	require for competence (predicted from homology) Unclear

Genomic Context

Location: 491865..503109

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KPU60_RS02530 (KPU60_02505)	-	492849..493640 (-)	792	WP_010706768.1	hypothetical protein	-
KPU60_RS02535 (KPU60_02510)	-	493804..494187 (+)	384	WP_002365398.1	YccF domain-containing protein	-
KPU60_RS02540 (KPU60_02515)	-	494276..494701 (+)	426	WP_002383201.1	Rrf2 family transcriptional regulator	-
KPU60_RS02545 (KPU60_02520)	-	494760..495389 (+)	630	WP_002365397.1	NAD(P)-dependent oxidoreductase	-
KPU60_RS02550 (KPU60_02525)	-	495468..496673 (-)	1206	WP_002367468.1	hypothetical protein	-
KPU60_RS02555 (KPU60_02530)	cinA	496865..498109 (+)	1245	WP_002365395.1	competence/damage-inducible protein A	Machinery gene
KPU60_RS02560 (KPU60_02535)	recA	498223..499269 (+)	1047	WP_002354860.1	recombinase RecA	Machinery gene
KPU60_RS02565 (KPU60_02540)	rny	499666..501222 (+)	1557	WP_002354863.1	ribonuclease Y	-
KPU60_RS02570 (KPU60_02545)	-	501382..502179 (+)	798	WP_002354864.1	TIGR00282 family metallophosphoesterase	-
KPU60_RS02575 (KPU60_02550)	-	502253..502639 (+)	387	WP_002359008.1	YlbF family regulator	-

Sequence

Protein

Download Length: 414 a.a. Molecular weight: 45193.29 Da Isoelectric Point: 4.6698

                                >NTDB_id=575714 KPU60_RS02555 WP_002365395.1 496865..498109(+) (cinA) [Enterococcus faecalis strain UAMS_EL56]

MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV

VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF

QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE

EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH

ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPLEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM

RGLDLLRRRIINKK

Nucleotide

Download Length: 1245 bp

                                >NTDB_id=575714 KPU60_RS02555 WP_002365395.1 496865..498109(+) (cinA) [Enterococcus faecalis strain UAMS_EL56]

ATGAAAGCAGAGATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA

AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA

CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT

GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA

GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATCGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG

CGGTTGGTTCTTTTGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC

CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG

CATTGGTGAATCCCAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA

AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA

GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT

GTTATTACAAAACGGACAAACCGTTACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG

CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT

GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC

TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCACTCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG

CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG

CGAGGATTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A855UKS7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
cinA	Streptococcus mutans UA159	52.632	100	0.531
cinA	Streptococcus mitis SK321	51.773	100	0.529
cinA	Streptococcus mitis NCTC 12261	51.537	100	0.527
cinA	Streptococcus pneumoniae TIGR4	50.827	100	0.519
cinA	Streptococcus pneumoniae D39	50.591	100	0.517
cinA	Streptococcus pneumoniae R6	50.355	100	0.514
cinA	Streptococcus pneumoniae Rx1	50.355	100	0.514
cinA	Bacillus subtilis subsp. subtilis str. 168	48.522	98.068	0.476
cinA	Streptococcus suis isolate S10	44.039	99.275	0.437

Detailed information NTG0575714