Detailed information NTG0575566

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: MPG06_RS04460
• Genome accession: NZ_CP094126
• Coordinates: 930830..933358 (-)
• Length: 842 a.a.
• NCBI ID: WP_245057128.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain Hpfe056
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 925830..938358

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MPG06_RS04440 (MPG06_04440)	comB10	926671..927873 (-)	1203	WP_245057120.1	DNA type IV secretion system protein ComB10	Machinery gene
MPG06_RS04445 (MPG06_04445)	-	927870..929540 (-)	1671	WP_245057123.1	TrbG/VirB9 family P-type conjugative transfer protein	-
MPG06_RS04450 (MPG06_04450)	-	929543..930706 (-)	1164	WP_245057126.1	VirB8/TrbF family protein	-
MPG06_RS04455 (MPG06_04455)	-	930699..930833 (-)	135	WP_000738749.1	hypothetical protein	-
MPG06_RS04460 (MPG06_04460)	comB4	930830..933358 (-)	2529	WP_245057128.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
MPG06_RS04465 (MPG06_04465)	-	933358..933594 (-)	237	WP_245057130.1	hypothetical protein	-
MPG06_RS04470 (MPG06_04470)	comB3	933606..933869 (-)	264	WP_001177712.1	hypothetical protein	Machinery gene
MPG06_RS04475 (MPG06_04475)	comB2	933880..934164 (-)	285	WP_000736478.1	TrbC/VirB2 family protein	Machinery gene
MPG06_RS04480 (MPG06_04480)	-	934161..934640 (-)	480	WP_195836226.1	hypothetical protein	-
MPG06_RS04485 (MPG06_04485)	-	934744..935532 (-)	789	WP_120945486.1	integrase	-
MPG06_RS04490 (MPG06_04490)	-	935707..936462 (+)	756	WP_245057133.1	ABC transporter permease	-

Sequence

Protein

• Length: 842 a.a.
• Molecular weight: 96916.74 Da
• Isoelectric Point: 8.8997

>NTDB_id=575566 MPG06_RS04460 WP_245057128.1 930830..933358(-) (comB4) [Helicobacter pylori strain Hpfe056]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSNKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNIELDLIFHIRSLGQFESLNFLKTKKKLTLSKIVKND
IDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYFSFFPNNANINPRMRNQTS
QVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGHTMIIGATGAGKTTLISYL
MMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQMAKVDSYDKHNDKIEDRTA
LLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEYYLKSSLFSSRMDSLDFKTRISTINTDS
ILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMINKEINKIITQARKANGVIVLALQDINQLSEVKNA
QSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNIIDVSLSSLGNYLQIFSSNS
SMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2529 bp

>NTDB_id=575566 MPG06_RS04460 WP_245057128.1 930830..933358(-) (comB4) [Helicobacter pylori strain Hpfe056]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCTATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAT
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACATTGAATTAGATTTAATCTTTCATATCC
GCTCTTTAGGGCAATTTGAAAGCTTGAATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGAT
ATTGATGATTATATAGAATTGGTGCAAGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAA
AAGTAAAGCAAAACTAGATAAGTCTTTAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAA
CCATAGGGCTAAAACCCTCTTATTTTTCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCC
CAAGTGATTGCCTCTTTAATCTTGTTTGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATC
TGTGTTTAAGAACCTAGACCATAGCCCTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCC
ATAATGTGGCACGAGTGGTAGGACATACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTG
ATGATGAGCGCTTTAAAATACCCTAACATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTA
TTTTGATGGGATTTATAATGAAGGCGAAAGCTTTCATATTAATCCTTTTTCATTAGAAGATAGCGCAAGTAACAGAGCCT
TTTTATTGCATTTTTATGCCCAAATGGCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCC
CTTTTAAACGCTATTGATACCATGTATAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACC
ACTCCCTTTTGATTTAAAAGAGTTTGTCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAATACT
ATTTAAAATCTTCCTTATTTTCTAGCCGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGC
ATTTTACACAATGATGATGACGCTGGGCTTTTAGCTTATTATGTGTTTCATAAGATGATTGATAGAGCTTTGAAAATCAA
TCGTGGGTTTTTATGTTTTATTGATGAGTTTAAATCTTACGCTCAAAATGAAATGATAAATAAAGAAATCAATAAAATCA
TCACGCAAGCTAGAAAGGCTAATGGGGTCATTGTTCTAGCCTTACAAGACATTAACCAACTTAGTGAAGTGAAAAACGCT
CAAAGCTTTATTAAAAATATGGGGCAATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATT
TGGCATTAGACTAAGCGATACAGAAAAACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACA
TGAATGATGGCTCATCTAACATTATAGATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCT
AGCATGGTAGAACATATTGAAAATCTTATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCA
AAAATTTGATGACAAAAAACACTTAGAAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-394)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (419-486)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.254	99.881	0.462