Detailed information NTG0575017

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: MPF92_RS06915
• Genome accession: NZ_CP094106
• Coordinates: 1458679..1461261 (-)
• Length: 860 a.a.
• NCBI ID: WP_245023761.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain Hpfe075
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1453679..1466261

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MPF92_RS06895 (MPF92_06895)	-	1454523..1455725 (-)	1203	Protein_1339	DNA type IV secretion system protein ComB10	-
MPF92_RS06900 (MPF92_06900)	-	1455722..1457392 (-)	1671	WP_245023759.1	TrbG/VirB9 family P-type conjugative transfer protein	-
MPF92_RS06905 (MPF92_06905)	-	1457389..1458555 (-)	1167	WP_245023760.1	VirB8/TrbF family protein	-
MPF92_RS06910 (MPF92_06910)	-	1458548..1458682 (-)	135	WP_000738749.1	hypothetical protein	-
MPF92_RS06915 (MPF92_06915)	comB4	1458679..1461261 (-)	2583	WP_245023761.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
MPF92_RS06920 (MPF92_06920)	-	1461261..1461497 (-)	237	WP_001183709.1	hypothetical protein	-
MPF92_RS06925 (MPF92_06925)	comB3	1461508..1461771 (-)	264	WP_001177712.1	hypothetical protein	Machinery gene
MPF92_RS06930 (MPF92_06930)	comB2	1461782..1462066 (-)	285	WP_000736478.1	TrbC/VirB2 family protein	Machinery gene
MPF92_RS06935 (MPF92_06935)	-	1462063..1462542 (-)	480	WP_195834060.1	hypothetical protein	-
MPF92_RS06940 (MPF92_06940)	-	1462646..1463434 (-)	789	WP_245023762.1	integrase	-
MPF92_RS06945 (MPF92_06945)	rpoD	1463620..1465647 (+)	2028	WP_245023763.1	RNA polymerase sigma factor RpoD	-

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 98973.96 Da
• Isoelectric Point: 8.4328

>NTDB_id=575017 MPF92_RS06915 WP_245023761.1 1458679..1461261(-) (comB4) [Helicobacter pylori strain Hpfe075]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLESYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSNKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2583 bp

>NTDB_id=575017 MPF92_RS06915 WP_245023761.1 1458679..1461261(-) (comB4) [Helicobacter pylori strain Hpfe075]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGAGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGAATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCTATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGTGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAGTTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAGCTTTCATATCAATCCTTTTTCATTAGAAGATAGCGCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTACGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTCAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACATAATGATGATGACGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATGATTGATAGAGCCTTGAAAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAGATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAAGCTAATGGG
GTGATTGTTTTAGCCTTACAAGATATTAACCAGCTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.206	97.791	0.462