Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   KM390_RS18880 Genome accession   NZ_CP076204
Coordinates   3644090..3644869 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus anthracis strain 3-IZSLT     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3609768..3683692 3644090..3644869 within 0


Gene organization within MGE regions


Location: 3609768..3683692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KM390_RS18730 (KM390_18745) - 3610112..3611782 (-) 1671 WP_000823085.1 ribonuclease J -
  KM390_RS18735 (KM390_18750) dapA 3612548..3613426 (-) 879 WP_000564761.1 4-hydroxy-tetrahydrodipicolinate synthase -
  KM390_RS18740 (KM390_18755) dapG 3613438..3614670 (-) 1233 WP_000692470.1 aspartate kinase -
  KM390_RS18745 (KM390_18760) asd 3614694..3615740 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  KM390_RS18750 (KM390_18765) dpaB 3615891..3616490 (-) 600 WP_001049484.1 dipicolinate synthase subunit B -
  KM390_RS18755 (KM390_18770) dpaA 3616487..3617389 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  KM390_RS18760 (KM390_18775) - 3617664..3617915 (-) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  KM390_RS18765 (KM390_18780) - 3618042..3619283 (-) 1242 WP_000592993.1 M16 family metallopeptidase -
  KM390_RS18770 (KM390_18785) - 3619370..3620269 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  KM390_RS18775 (KM390_18790) pnp 3620421..3622559 (-) 2139 WP_000076750.1 polyribonucleotide nucleotidyltransferase -
  KM390_RS18780 (KM390_18795) rpsO 3622720..3622989 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  KM390_RS18785 (KM390_18800) ribF 3623090..3624061 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  KM390_RS18790 (KM390_18805) truB 3624105..3625028 (-) 924 WP_000399357.1 tRNA pseudouridine(55) synthase TruB -
  KM390_RS18795 (KM390_18810) rbfA 3625115..3625471 (-) 357 WP_000776446.1 30S ribosome-binding factor RbfA -
  KM390_RS18800 (KM390_18815) - 3625487..3625768 (-) 282 WP_000582364.1 DUF503 domain-containing protein -
  KM390_RS18805 (KM390_18820) infB 3625765..3627825 (-) 2061 WP_000036339.1 translation initiation factor IF-2 -
  KM390_RS18810 (KM390_18825) - 3627830..3628141 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  KM390_RS18815 (KM390_18830) rnpM 3628142..3628414 (-) 273 WP_000071128.1 RNase P modulator RnpM -
  KM390_RS18820 (KM390_18835) nusA 3628426..3629532 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  KM390_RS18825 (KM390_18840) rimP 3629550..3630020 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  KM390_RS18830 (KM390_18845) - 3630353..3634654 (-) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  KM390_RS18835 (KM390_18850) - 3634779..3636479 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  KM390_RS18840 (KM390_18855) rseP 3636589..3637845 (-) 1257 WP_001090228.1 RIP metalloprotease RseP -
  KM390_RS18845 (KM390_18860) dxr 3637862..3639004 (-) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  KM390_RS18850 (KM390_18865) cdsA 3639028..3639819 (-) 792 WP_000813581.1 phosphatidate cytidylyltransferase -
  KM390_RS18855 (KM390_18870) uppS 3639837..3640613 (-) 777 WP_000971303.1 isoprenyl transferase -
  KM390_RS18860 (KM390_18875) frr 3640699..3641256 (-) 558 WP_000531503.1 ribosome recycling factor -
  KM390_RS18865 (KM390_18880) pyrH 3641259..3641981 (-) 723 WP_000042663.1 UMP kinase -
  KM390_RS18870 (KM390_18885) tsf 3642048..3642935 (-) 888 WP_001018581.1 translation elongation factor Ts -
  KM390_RS18875 (KM390_18890) rpsB 3643039..3643740 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  KM390_RS18880 (KM390_18895) codY 3644090..3644869 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  KM390_RS18885 (KM390_18900) hslU 3644947..3646338 (-) 1392 WP_000550088.1 ATP-dependent protease ATPase subunit HslU -
  KM390_RS18890 (KM390_18905) hslV 3646361..3646903 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  KM390_RS18895 (KM390_18910) xerC 3646946..3647845 (-) 900 WP_001101226.1 tyrosine recombinase XerC -
  KM390_RS18900 (KM390_18915) trmFO 3647911..3649215 (-) 1305 WP_003161605.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  KM390_RS18905 (KM390_18920) topA 3649266..3651344 (-) 2079 WP_001286969.1 type I DNA topoisomerase -
  KM390_RS18910 (KM390_18925) dprA 3651489..3652237 (-) 749 Protein_3698 DNA-processing protein DprA -
  KM390_RS18915 (KM390_18930) sucD 3652445..3653347 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  KM390_RS18920 (KM390_18935) sucC 3653368..3654528 (-) 1161 WP_001020786.1 ADP-forming succinate--CoA ligase subunit beta -
  KM390_RS18925 (KM390_18940) rnhB 3654722..3655495 (-) 774 WP_001174712.1 ribonuclease HII -
  KM390_RS18930 (KM390_18945) ylqF 3655547..3656437 (-) 891 WP_000236707.1 ribosome biogenesis GTPase YlqF -
  KM390_RS18935 (KM390_18950) lepB 3656458..3657009 (-) 552 WP_000711857.1 signal peptidase I -
  KM390_RS18940 (KM390_18955) rplS 3657111..3657455 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  KM390_RS18945 (KM390_18960) trmD 3657602..3658336 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  KM390_RS18950 (KM390_18965) rimM 3658336..3658851 (-) 516 WP_000170269.1 ribosome maturation factor RimM -
  KM390_RS18955 (KM390_18970) - 3658972..3659199 (-) 228 WP_000737398.1 KH domain-containing protein -
  KM390_RS18960 (KM390_18975) rpsP 3659214..3659486 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  KM390_RS18965 (KM390_18980) ffh 3659587..3660936 (-) 1350 WP_000863456.1 signal recognition particle protein -
  KM390_RS18970 (KM390_18985) - 3660949..3661281 (-) 333 WP_000891062.1 putative DNA-binding protein -
  KM390_RS18975 (KM390_18990) ftsY 3661415..3662404 (-) 990 WP_000007650.1 signal recognition particle-docking protein FtsY -
  KM390_RS18980 (KM390_18995) smc 3662420..3665989 (-) 3570 WP_000478985.1 chromosome segregation protein SMC -
  KM390_RS18985 (KM390_19000) rncS 3666136..3666873 (-) 738 WP_001146873.1 ribonuclease III -
  KM390_RS18990 (KM390_19005) acpP 3666932..3667165 (-) 234 WP_000786062.1 acyl carrier protein -
  KM390_RS18995 (KM390_19010) fabG 3667235..3667975 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  KM390_RS19000 (KM390_19015) fabD 3667975..3668919 (-) 945 WP_000516958.1 ACP S-malonyltransferase -
  KM390_RS19005 (KM390_19020) plsX 3668934..3669926 (-) 993 WP_000684111.1 phosphate acyltransferase PlsX -
  KM390_RS19010 (KM390_19025) fapR 3669923..3670516 (-) 594 WP_000747352.1 transcription factor FapR -
  KM390_RS19015 (KM390_19030) recG 3670605..3672653 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  KM390_RS19020 (KM390_19035) - 3672943..3674619 (-) 1677 WP_000027136.1 DAK2 domain-containing protein -
  KM390_RS19025 (KM390_19040) - 3674642..3675004 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  KM390_RS19030 (KM390_19045) rpmB 3675383..3675571 (+) 189 WP_000124778.1 50S ribosomal protein L28 -
  KM390_RS19035 (KM390_19050) spoVM 3675644..3675724 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  KM390_RS19040 (KM390_19055) - 3675791..3676471 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  KM390_RS19045 (KM390_19060) rpe 3676571..3677215 (-) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  KM390_RS19050 (KM390_19065) rsgA 3677218..3678099 (-) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  KM390_RS19055 (KM390_19070) prkC 3678368..3680341 (-) 1974 WP_000904759.1 serine/threonine protein kinase PrkC -
  KM390_RS19060 (KM390_19075) - 3680350..3681102 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  KM390_RS19065 (KM390_19080) rlmN 3681107..3682195 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  KM390_RS19070 (KM390_19085) rsmB 3682200..3683534 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=573479 KM390_RS18880 WP_000421288.1 3644090..3644869(-) (codY) [Bacillus anthracis strain 3-IZSLT]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=573479 KM390_RS18880 WP_000421288.1 3644090..3644869(-) (codY) [Bacillus anthracis strain 3-IZSLT]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459