Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   - Genome accession   NC_021486
Coordinates   65093..65140 (+) Length   16 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus agalactiae ILRI005     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context


Location: 60093..70140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MSA_RS00390 (MSA_850) - 60839..61096 (+) 258 WP_016480175.1 hypothetical protein -
  MSA_RS00395 (MSA_860) - 61517..62566 (+) 1050 WP_016480176.1 DUF6287 domain-containing protein -
  MSA_RS00400 (MSA_870) purB 62652..63950 (+) 1299 WP_016480177.1 adenylosuccinate lyase -
  MSA_RS00405 (MSA_880) - 64103..65011 (+) 909 WP_016480178.1 XRE family transcriptional regulator -
  - comS 65093..65140 (+) 48 - - Regulator
  MSA_RS00410 (MSA_890) ruvB 65210..66208 (+) 999 WP_016480179.1 Holliday junction branch migration DNA helicase RuvB -
  MSA_RS00415 (MSA_900) - 66360..66797 (+) 438 WP_016480180.1 low molecular weight protein-tyrosine-phosphatase -
  MSA_RS00420 (MSA_910) - 66804..67184 (+) 381 WP_000787702.1 membrane protein -
  MSA_RS00425 (MSA_920) - 67181..68959 (+) 1779 WP_016480181.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 16 a.a.        Molecular weight: 1923.31 Da        Isoelectric Point: 9.1500

>NTDB_id=566 65093..65140(+) (comS) [Streptococcus agalactiae ILRI005]
MFKVFFTVITGGFWWG

Nucleotide


Download         Length: 48 bp        

>NTDB_id=566 65093..65140(+) (comS) [Streptococcus agalactiae ILRI005]
ATGTTTAAAGTATTTTTTACAGTAATAACAGGGGGTTTCTGGTGGGGA

XIP


This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

TGGFWWG


Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Latilactobacillus sakei subsp. sakei 23K

50

75

0.375


Multiple sequence alignment