Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   HD73_RS20445 Genome accession   NC_020238
Coordinates   3973762..3974541 (-) Length   259 a.a.
NCBI ID   WP_000421290.1    Uniprot ID   A0A9W5VKA1
Organism   Bacillus thuringiensis serovar kurstaki str. HD73     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3958316..4015987 3973762..3974541 within 0


Gene organization within MGE regions


Location: 3958316..4015987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HD73_RS20390 (HD73_4100) rimP 3959218..3959688 (-) 471 WP_000359096.1 ribosome maturation factor RimP -
  HD73_RS20395 (HD73_4101) - 3960025..3964326 (-) 4302 WP_000060004.1 PolC-type DNA polymerase III -
  HD73_RS20400 (HD73_4102) - 3964451..3966151 (-) 1701 WP_000814333.1 proline--tRNA ligase -
  HD73_RS20405 (HD73_4103) rseP 3966261..3967517 (-) 1257 WP_001090245.1 RIP metalloprotease RseP -
  HD73_RS20410 (HD73_4104) dxr 3967535..3968677 (-) 1143 WP_000790372.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  HD73_RS20415 (HD73_4105) cdsA 3968701..3969492 (-) 792 WP_000813592.1 phosphatidate cytidylyltransferase -
  HD73_RS20420 (HD73_4106) uppS 3969510..3970286 (-) 777 WP_000971296.1 isoprenyl transferase -
  HD73_RS20425 (HD73_4107) frr 3970372..3970929 (-) 558 WP_000531501.1 ribosome recycling factor -
  HD73_RS20430 (HD73_4108) pyrH 3970932..3971654 (-) 723 WP_000042668.1 UMP kinase -
  HD73_RS20435 (HD73_4109) tsf 3971721..3972608 (-) 888 WP_001018578.1 translation elongation factor Ts -
  HD73_RS20440 (HD73_4110) rpsB 3972712..3973413 (-) 702 WP_000111485.1 30S ribosomal protein S2 -
  HD73_RS20445 (HD73_4111) codY 3973762..3974541 (-) 780 WP_000421290.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  HD73_RS20450 (HD73_4112) hslU 3974619..3976010 (-) 1392 WP_000550087.1 ATP-dependent protease ATPase subunit HslU -
  HD73_RS20455 (HD73_4113) hslV 3976033..3976575 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  HD73_RS20460 (HD73_4114) xerC 3976618..3977517 (-) 900 WP_001101241.1 tyrosine recombinase XerC -
  HD73_RS20465 (HD73_4115) trmFO 3977583..3978887 (-) 1305 WP_000213002.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  HD73_RS20470 (HD73_4116) topA 3978936..3981014 (-) 2079 WP_001286963.1 type I DNA topoisomerase -
  HD73_RS20475 (HD73_4117) dprA 3981159..3982028 (-) 870 WP_000818039.1 DNA-processing protein DprA -
  HD73_RS20480 (HD73_4118) sucD 3982116..3983018 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  HD73_RS20485 (HD73_4119) sucC 3983038..3984198 (-) 1161 WP_001020791.1 ADP-forming succinate--CoA ligase subunit beta -
  HD73_RS20490 (HD73_4120) - 3984393..3985166 (-) 774 WP_001193513.1 ribonuclease HII -
  HD73_RS20495 (HD73_4121) ylqF 3985223..3986113 (-) 891 WP_000236702.1 ribosome biogenesis GTPase YlqF -
  HD73_RS20500 (HD73_4122) lepB 3986134..3986685 (-) 552 WP_000711851.1 signal peptidase I -
  HD73_RS20505 (HD73_4123) rplS 3986787..3987131 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  HD73_RS20510 (HD73_4124) trmD 3987278..3988012 (-) 735 WP_000686903.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  HD73_RS20515 (HD73_4125) rimM 3988012..3988527 (-) 516 WP_000170278.1 ribosome maturation factor RimM -
  HD73_RS20520 (HD73_4126) - 3988648..3988875 (-) 228 WP_000737401.1 KH domain-containing protein -
  HD73_RS20525 (HD73_4127) rpsP 3988890..3989162 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  HD73_RS20530 (HD73_4128) ffh 3989264..3990613 (-) 1350 WP_000863460.1 signal recognition particle protein -
  HD73_RS20535 (HD73_4129) - 3990626..3990958 (-) 333 WP_000891062.1 putative DNA-binding protein -
  HD73_RS20540 (HD73_4130) ftsY 3991092..3992081 (-) 990 WP_000007655.1 signal recognition particle-docking protein FtsY -
  HD73_RS20545 (HD73_4131) smc 3992097..3995204 (-) 3108 Protein_3997 chromosome segregation protein SMC -
  HD73_RS20550 (HD73_4132) ltrA 3995302..3997107 (-) 1806 WP_000108316.1 group II intron reverse transcriptase/maturase -
  HD73_RS20555 (HD73_4133) - 3997811..3998272 (-) 462 Protein_3999 AAA family ATPase -
  HD73_RS20560 (HD73_4134) rncS 3998419..3999156 (-) 738 WP_001146875.1 ribonuclease III -
  HD73_RS20565 (HD73_4135) acpP 3999215..3999448 (-) 234 WP_000786062.1 acyl carrier protein -
  HD73_RS20570 (HD73_4136) fabG 3999518..4000258 (-) 741 WP_000911768.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  HD73_RS20575 (HD73_4137) fabD 4000258..4001202 (-) 945 WP_000515905.1 ACP S-malonyltransferase -
  HD73_RS20580 (HD73_4138) plsX 4001217..4002209 (-) 993 WP_000684098.1 phosphate acyltransferase PlsX -
  HD73_RS20585 (HD73_4139) fapR 4002206..4002799 (-) 594 WP_000747349.1 transcription factor FapR -
  HD73_RS20590 (HD73_4140) recG 4002888..4004936 (-) 2049 WP_001000811.1 ATP-dependent DNA helicase RecG -
  HD73_RS20595 (HD73_4141) - 4005227..4006903 (-) 1677 WP_000027129.1 DAK2 domain-containing protein -
  HD73_RS20600 (HD73_4142) - 4006926..4007288 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  HD73_RS20605 (HD73_4143) rpmB 4007665..4007853 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  HD73_RS20610 spoVM 4007927..4008007 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  HD73_RS20615 (HD73_4144) - 4008074..4008754 (-) 681 WP_002132739.1 thiamine diphosphokinase -
  HD73_RS20620 (HD73_4145) rpe 4008824..4009468 (-) 645 WP_000589974.1 ribulose-phosphate 3-epimerase -
  HD73_RS20625 (HD73_4146) rsgA 4009471..4010352 (-) 882 WP_001113932.1 ribosome small subunit-dependent GTPase A -
  HD73_RS20630 (HD73_4147) pknB 4010599..4012572 (-) 1974 WP_000904748.1 Stk1 family PASTA domain-containing Ser/Thr kinase -
  HD73_RS20635 (HD73_4148) - 4012581..4013333 (-) 753 WP_000648703.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  HD73_RS20640 (HD73_4149) rlmN 4013338..4014426 (-) 1089 WP_000450541.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  HD73_RS20645 (HD73_4150) rsmB 4014431..4015765 (-) 1335 WP_001249668.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28793.05 Da        Isoelectric Point: 4.7165

>NTDB_id=55948 HD73_RS20445 WP_000421290.1 3973762..3974541(-) (codY) [Bacillus thuringiensis serovar kurstaki str. HD73]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=55948 HD73_RS20445 WP_000421290.1 3973762..3974541(-) (codY) [Bacillus thuringiensis serovar kurstaki str. HD73]
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGGAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCAAACGTATTCGTAGTTAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAAAACGAACGCATGAAGCAAATGCTTGCAGAACGTCAATTCCCAGAAGAATATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTGAACAGTGCTTACACAGCATTCCCAGTAGAAAACAGAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATCCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAGTTAGAAGCGAT
TGAGCACATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GTTCTGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.467

100

0.815
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment