Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   INT76_RS02540 Genome accession   NZ_CP073084
Coordinates   516636..517472 (-) Length   278 a.a.
NCBI ID   WP_212571868.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 511636..522472
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS02520 (INT76_02520) hisG 512691..513338 (-) 648 WP_212571862.1 ATP phosphoribosyltransferase -
  INT76_RS02525 (INT76_02525) - 513340..514314 (-) 975 WP_212571864.1 ATP phosphoribosyltransferase regulatory subunit -
  INT76_RS02530 (INT76_02530) hisC 514280..515362 (-) 1083 WP_212572996.1 histidinol-phosphate transaminase -
  INT76_RS02535 (INT76_02535) - 515827..516573 (+) 747 WP_212571867.1 PHP domain-containing protein -
  INT76_RS02540 (INT76_02540) endA 516636..517472 (-) 837 WP_212571868.1 DNA/RNA non-specific endonuclease Machinery gene
  INT76_RS02545 (INT76_02545) - 517503..517694 (-) 192 WP_212571870.1 DNA-directed RNA polymerase subunit beta -
  INT76_RS02550 (INT76_02550) murA 517698..518969 (-) 1272 WP_212571872.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  INT76_RS02555 (INT76_02555) - 519003..519233 (-) 231 WP_212571873.1 DUF1146 family protein -
  INT76_RS02560 (INT76_02560) - 519360..519776 (-) 417 WP_212572997.1 F0F1 ATP synthase subunit epsilon -
  INT76_RS02565 (INT76_02565) atpD 519786..521192 (-) 1407 WP_212571874.1 F0F1 ATP synthase subunit beta -
  INT76_RS02570 (INT76_02570) - 521210..522088 (-) 879 WP_212571875.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 278 a.a.        Molecular weight: 30124.26 Da        Isoelectric Point: 4.9918

>NTDB_id=557823 INT76_RS02540 WP_212571868.1 516636..517472(-) (endA) [Streptococcus oriscaviae strain HKU75]
MAKKRLGKQVSSAISLLVTVLIIAGAYLLNEEPTQEQSSSYFVNQSLASEAAPSEELASSVLTESVRKQLGESIEWNGAG
AFVINGNVTKLDASVSSMPYAENKTKAAQGETVPTVANALLTKATRQYKSREETGNGSTSWTPAGWHQIQNLEGEYDHAV
DRGHLLAYSLVGSLKGFDASTSNPANIAVQTAWANQSNQEDATGQNYYETQIRKALDQNKRVRYHVTLIYANEEDLVAVG
SHLEAKSSDGSLEFNVFIPNVQSGLSIDYHSGEIHVNQ

Nucleotide


Download         Length: 837 bp        

>NTDB_id=557823 INT76_RS02540 WP_212571868.1 516636..517472(-) (endA) [Streptococcus oriscaviae strain HKU75]
ATGGCAAAAAAACGGTTAGGAAAACAAGTTTCCAGTGCAATTAGTCTTTTAGTGACGGTCCTCATCATTGCAGGGGCTTA
TTTACTCAATGAAGAACCTACGCAGGAGCAAAGTAGCAGCTACTTTGTCAATCAGTCACTAGCCAGTGAGGCAGCCCCTT
CTGAGGAACTAGCTAGCTCTGTTTTGACAGAATCTGTCAGAAAACAACTGGGAGAGTCTATCGAATGGAATGGTGCAGGG
GCCTTTGTAATCAATGGGAATGTCACAAAATTGGATGCTTCCGTATCCAGCATGCCCTACGCTGAAAACAAGACCAAGGC
TGCTCAGGGAGAAACGGTTCCAACAGTGGCCAACGCCTTGCTGACTAAGGCGACCCGTCAATACAAGAGCCGTGAAGAAA
CTGGCAATGGGTCTACTTCTTGGACACCCGCAGGCTGGCATCAGATTCAAAATCTGGAAGGAGAGTATGACCATGCTGTT
GACCGTGGACATTTGCTGGCTTACTCCTTAGTGGGAAGCCTTAAGGGCTTTGATGCTTCTACGAGCAATCCAGCCAATAT
CGCTGTCCAAACAGCTTGGGCCAACCAGTCCAATCAGGAGGACGCAACCGGACAAAACTACTACGAAACCCAAATTCGTA
AGGCTTTGGATCAGAACAAGCGAGTTCGCTATCATGTCACCCTTATCTATGCCAATGAGGAAGATTTGGTGGCAGTTGGC
AGTCACTTAGAAGCTAAGTCTTCGGATGGCAGTTTGGAATTTAATGTCTTCATTCCCAATGTCCAAAGTGGTCTCAGTAT
AGACTACCATAGCGGAGAAATTCATGTGAATCAATAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(80-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

65.354

91.367

0.597
  endA Streptococcus pneumoniae D39

65.354

91.367

0.597
  endA Streptococcus pneumoniae R6

65.354

91.367

0.597
  endA Streptococcus pneumoniae TIGR4

65.354

91.367

0.597