Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   J9539_RS12065 Genome accession   NZ_CP072878
Coordinates   2481908..2483149 (-) Length   413 a.a.
NCBI ID   WP_002296026.1    Uniprot ID   A0AAV3GRJ1
Organism   Enterococcus faecium strain F88     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2476908..2488149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J9539_RS12050 (J9539_12050) proC 2477898..2478704 (+) 807 WP_002296027.1 pyrroline-5-carboxylate reductase -
  J9539_RS12055 (J9539_12055) rny 2478783..2480339 (-) 1557 WP_002287336.1 ribonuclease Y -
  J9539_RS12060 (J9539_12060) recA 2480750..2481799 (-) 1050 WP_002287328.1 recombinase RecA Machinery gene
  J9539_RS12065 (J9539_12065) cinA 2481908..2483149 (-) 1242 WP_002296026.1 competence/damage-inducible protein A Machinery gene
  J9539_RS12070 (J9539_12070) pgsA 2483389..2483967 (-) 579 WP_002296025.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  J9539_RS12075 (J9539_12075) - 2484176..2485099 (-) 924 WP_218210458.1 RodZ domain-containing protein -
  J9539_RS12080 (J9539_12080) - 2485838..2487124 (-) 1287 WP_002287425.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45415.76 Da        Isoelectric Point: 4.6507

>NTDB_id=556540 J9539_RS12065 WP_002296026.1 2481908..2483149(-) (cinA) [Enterococcus faecium strain F88]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=556540 J9539_RS12065 WP_002296026.1 2481908..2483149(-) (cinA) [Enterococcus faecium strain F88]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAGACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

51.19

100

0.521
  cinA Streptococcus mutans UA159

51.566

100

0.518
  cinA Streptococcus pneumoniae TIGR4

50.952

100

0.518
  cinA Streptococcus pneumoniae D39

50.714

100

0.516
  cinA Streptococcus pneumoniae R6

50.714

100

0.516
  cinA Streptococcus pneumoniae Rx1

50.714

100

0.516
  cinA Streptococcus mitis NCTC 12261

50.714

100

0.516
  cinA Bacillus subtilis subsp. subtilis str. 168

47.573

99.758

0.475
  cinA Streptococcus suis isolate S10

41.787

100

0.419