Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   L1A14_RS02240 Genome accession   NZ_CP090883
Coordinates   419948..422284 (+) Length   778 a.a.
NCBI ID   WP_001035034.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LE4448     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 414948..427284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A14_RS02220 (L1A14_02220) lepB 417411..418025 (-) 615 WP_001083986.1 signal peptidase I -
  L1A14_RS02225 (L1A14_02225) rnhC 418029..418910 (-) 882 WP_000146855.1 ribonuclease HIII -
  L1A14_RS02230 (L1A14_02230) zapA 418997..419299 (+) 303 WP_000002019.1 cell division protein ZapA -
  L1A14_RS02235 (L1A14_02235) - 419296..419844 (+) 549 WP_000622953.1 CvpA family protein -
  L1A14_RS02240 (L1A14_02240) mutS/mutS2 419948..422284 (+) 2337 WP_001035034.1 endonuclease MutS2 Machinery gene
  L1A14_RS02245 (L1A14_02245) - 422627..423949 (+) 1323 WP_000891497.1 sodium:alanine symporter family protein -
  L1A14_RS02250 (L1A14_02250) - 424167..424715 (+) 549 WP_000206761.1 carboxymuconolactone decarboxylase family protein -
  L1A14_RS02255 (L1A14_02255) - 424825..425724 (+) 900 WP_000735956.1 TDT family transporter -
  L1A14_RS02260 (L1A14_02260) serS 425749..427023 (-) 1275 WP_000884256.1 serine--tRNA ligase -

Sequence

Protein


Download         Length: 778 a.a.        Molecular weight: 87639.61 Da        Isoelectric Point: 6.8352

>NTDB_id=556474 L1A14_RS02240 WP_001035034.1 419948..422284(+) (mutS/mutS2) [Streptococcus pneumoniae strain LE4448]
MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEM
GADLNIEEFLLLKRVLLTSRELQSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADER
YEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQD
LTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVN
QHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPG
RSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETE
LNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSY
GQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG

Nucleotide


Download         Length: 2337 bp        

>NTDB_id=556474 L1A14_RS02240 WP_001035034.1 419948..422284(+) (mutS/mutS2) [Streptococcus pneumoniae strain LE4448]
ATGAATAAGAAAATATTAGAAACATTAGAGTTCGATAAGGTCAAGGCCTTGTTTGAGCCTCATTTGTTGACCGAGCAGGG
CTTGGAGCAATTGAGACAGCTGGCTCCGACTGCCAAAGCAGATAAAATCAAACAGGCTTTTGCTGAGATGAAAGAAATGC
AGGCTCTTTTCGTCGAGCAACCGCATTTTACTATTCTCTCAACTAAGGAAATTGCAGGAGTCTGCAAGAGGTTGGAGATG
GGAGCGGATCTCAATATCGAGGAGTTCCTACTCTTGAAACGCGTGCTTCTTACCAGCCGAGAACTTCAAAGTTTTTACGC
CAATCTGGAAAATGTCAGCTTGGAAGAATTAGCCCTTTGGTTTGAGAAATTACATGATTTTCCGCAATTACAAGGAAATC
TTCAGGCCTTTAATGATGCGGGTTTCATTGAAAATTTTGCCAGTGAAGAATTGGCGCGAATCCGTCGAAAAATACATGAT
AGCGAGAGTCAGGTACGCGATGTTTTACAAGACTTGCTCAAGCAAAAAGCGCAGATGTTGACGGAAGGAATTGTTGCTAG
CAGAAATGGCCGTCAGGTTTTACCAGTCAAAAACACCTACCGCAATAAGATTGCAGGTGTCGTTCATGATATTTCTGCTA
GTGGAAACACCGTCTATATCGAACCACGTGAGGTAGTCAAACTGAGCGAAGAAATTGCTAGTCTGCGAGCAGATGAGCGC
TATGAAATGCTTCGCATTCTCCAAGAAATTTCTGAGCGTGTCCGCCCTCATGCGGCTGAGATTGCTAATGACGCTTGGAT
TATCGGTCATCTGGACTTGATTCGTGCCAAGGTTCGATTTATCCAAGAAAGACAAGCAGTCGTGCCTCAGCTGTCAGAAA
ATCAAGAGATTCAACTGCTCCATGTCTGCCATCCTTTGGTCAAAAATGCCGTCGCAAATGATGTCTATTTTGGTCAAGAT
TTAACAGCTATTGTCATTACAGGTCCCAATACAGGTGGGAAGACCATCATGCTCAAAACTCTGGGCTTGACACAGGTCAT
GGCCCAGTCAGGATTGCCGATTTTAGCAGACAAGGGAAGTCGTGTTGGTATTTTTGAAGAAATCTTTGCTGATATTGGAG
ATGAGCAGTCTATTGAGCAGAGCTTGTCTACCTTCTCTAGCCATATGACCAATATCGTGGATATTCTTGGCAAGGTCAAC
CAACATTCACTCTTACTTTTGGATGAGTTGGGGGCTGGTACTGATCCCCAAGAGGGAGCAGCCCTTGCCATGGCTATTCT
GGAGGACCTTCGCCTGCGTCAAATCAAGACCATGGCGACGACCCACTATCCAGAACTCAAGGCCTACGGTATTGAGACAG
CCTTTGTGCAAAATGCCAGTATGGAGTTTGATACTGCAACTCTTCGCCCGACCTATCGCTTTATGCAGGGTGTTCCTGGC
CGAAGTAATGCCTTTGAAATTGCCAAACGTCTAGGCCTATCTGAAGTTATCGTAGGAGATGCCAGTCAGCAGATCGATCA
GGACAATGACGTCAATCGTATCATTGAGCAACTAGAAGAGCAGACGCTGGAAAGCCGCAAACGCTTGGACAATATCCGTG
AGGTGGAGCAAGAAAATCTCAAGATGAACCGTGTGCTAAAAAAACTCTACAACGAGCTTAATCGTGAAAAGGAAACCGAG
CTTAACAAGGCGCGTGAACAGGCTGCTGAGATTGTGGATATGGCCCTAAGTGAAAGTGACCAGATTCTCAAAAATCTCCA
CAGTAAATCCCAACTCAAGCCCCACGAAATCATTGAAGCCAAAGCCAAGTTGAAAAAATTGGCTCCTGAAAAAGTGGACT
TGTCTAAAAACAAGGTCCTTCAAAAGGCCAAGAAAAAACGAGCTCCAAAGGTGGGAGATGATATCGTGGTTCTCAGTTAT
GGTCAGCGTGGTACCTTGACCAGTCAACTCAAGGACGGCCGCTGGGAAGCCCAAGTTGGCTTGATTAAGATGACCTTGGA
AGAGAAAGAGTTTGATCTTGTTCAAGCCCAGCAAGAAAAACCAGTCAAGAAGAAACAGGTCAATGTTGTGAAACGAACTT
CTGGGCGAGGACCTCAAGCTAGACTGGATCTTCGAGGCAAGCGCTATGAAGAAGCCATGAATGAGCTAGATACCTTCATC
GACCAAGCCTTGCTTAACAATATGGCTCAAGTTGATATCATCCATGGTATCGGAACAGGAGTCATCCGTGAAGGAGTTAC
CAAATACTTGCAAAGAAACAAACATGTCAAGAGTTTCGGCTATGCCCCACAAAATGCTGGAGGCAGTGGTGCGACTATTG
TCACTTTTAAAGGATAG

Domains

Predicted by InterProScan.

Smr domain (Smr)

(702-777)

MutS domain V (MutS_V)

(324-506)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.582

100

0.413