Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   M3B_RS00610 Genome accession   NZ_AP014596
Coordinates   98832..99116 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain M3-b     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 93832..104116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M3B_RS00585 (M3B_0117) - 95778..96143 (+) 366 WP_002986560.1 DUF1033 family protein -
  M3B_RS00590 (M3B_0118) comGA 96236..97174 (+) 939 WP_011054114.1 competence type IV pilus ATPase ComGA Machinery gene
  M3B_RS00595 (M3B_0119) comGB 97110..98144 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  M3B_RS00600 (M3B_0120) comGC 98146..98472 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  M3B_RS00605 (M3B_0121) comGD 98447..98875 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  M3B_RS00610 comGE 98832..99116 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  M3B_RS00615 (M3B_0123) comGF 99109..99543 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  M3B_RS00620 (M3B_0124) comGG 99527..99853 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  M3B_RS00625 (M3B_0125) comGH 99951..100904 (+) 954 WP_011054117.1 class I SAM-dependent methyltransferase Machinery gene
  M3B_RS00630 (M3B_0126) - 100963..102159 (+) 1197 WP_010921803.1 acetate kinase -
  M3B_RS00635 (M3B_0127) - 102345..102653 (+) 309 WP_011054118.1 hypothetical protein -
  M3B_RS00640 (M3B_0128) proC 102736..103506 (-) 771 WP_002992745.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=55619 M3B_RS00610 WP_002987779.1 98832..99116(+) (comGE) [Streptococcus pyogenes strain M3-b]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=55619 M3B_RS00610 WP_002987779.1 98832..99116(+) (comGE) [Streptococcus pyogenes strain M3-b]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTGAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383