Detailed information NTG0555560

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: J7U34_RS05745
• Genome accession: NZ_CP072778
• Coordinates: 1101934..1102815 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24748
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1096934..1107815

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U34_RS05720 (J7U34_05695)	vicR	1097638..1098345 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7U34_RS05725 (J7U34_05700)	-	1098872..1099639 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
J7U34_RS05730 (J7U34_05705)	-	1099651..1100484 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
J7U34_RS05735 (J7U34_05710)	-	1100502..1101200 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
J7U34_RS05740 (J7U34_05715)	-	1101212..1101862 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7U34_RS05745 (J7U34_05720)	endA	1101934..1102815 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
J7U34_RS05750 (J7U34_05725)	-	1102877..1103065 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
J7U34_RS05755 (J7U34_05730)	murA	1103067..1104338 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J7U34_RS05760 (J7U34_05735)	-	1104408..1104644 (-)	237	WP_002946959.1	DUF1146 family protein	-
J7U34_RS05765 (J7U34_05740)	galE	1104832..1105845 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
J7U34_RS05770 (J7U34_05745)	-	1105860..1106315 (-)	456	WP_024009932.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=555560 J7U34_RS05745 WP_011681210.1 1101934..1102815(-) (endA) [Streptococcus thermophilus strain S24748]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=555560 J7U34_RS05745 WP_011681210.1 1101934..1102815(-) (endA) [Streptococcus thermophilus strain S24748]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594