Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   LZ178_RS06560 Genome accession   NZ_CP090375
Coordinates   1363248..1364021 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain GD4SA108-1     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1358248..1369021
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LZ178_RS06540 (LZ178_06525) trmFO 1358592..1359899 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  LZ178_RS06545 (LZ178_06530) xerC 1360316..1361212 (+) 897 WP_001015606.1 tyrosine recombinase XerC -
  LZ178_RS06550 (LZ178_06535) hslV 1361209..1361754 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  LZ178_RS06555 (LZ178_06540) hslU 1361820..1363223 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  LZ178_RS06560 (LZ178_06545) codY 1363248..1364021 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  LZ178_RS06565 (LZ178_06550) - 1364072..1364164 (+) 93 WP_001790530.1 hypothetical protein -
  LZ178_RS06570 (LZ178_06555) rpsB 1364363..1365130 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  LZ178_RS06575 (LZ178_06560) - 1365164..1365277 (+) 114 WP_001789890.1 hypothetical protein -
  LZ178_RS06580 (LZ178_06565) tsf 1365312..1366193 (+) 882 WP_000201387.1 translation elongation factor Ts -
  LZ178_RS06585 (LZ178_06570) pyrH 1366330..1367052 (+) 723 WP_000057330.1 UMP kinase -
  LZ178_RS06590 (LZ178_06575) frr 1367071..1367625 (+) 555 WP_001280006.1 ribosome recycling factor -
  LZ178_RS06595 (LZ178_06580) - 1367998..1368768 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=553784 LZ178_RS06560 WP_000055337.1 1363248..1364021(+) (codY) [Staphylococcus aureus strain GD4SA108-1]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=553784 LZ178_RS06560 WP_000055337.1 1363248..1364021(+) (codY) [Staphylococcus aureus strain GD4SA108-1]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTTATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAG

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428