Detailed information NTG0553165

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: J7T81_RS05750
• Genome accession: NZ_CP072439
• Coordinates: 1104069..1104950 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24732
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1099069..1109950

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T81_RS05725 (J7T81_05705)	vicR	1099773..1100480 (-)	708	WP_011681206.1	response regulator YycF	Regulator
J7T81_RS05730 (J7T81_05710)	-	1101007..1101774 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
J7T81_RS05735 (J7T81_05715)	-	1101786..1102619 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
J7T81_RS05740 (J7T81_05720)	-	1102637..1103335 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
J7T81_RS05745 (J7T81_05725)	-	1103347..1103997 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
J7T81_RS05750 (J7T81_05730)	endA	1104069..1104950 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
J7T81_RS05755 (J7T81_05735)	-	1105012..1105200 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
J7T81_RS05760 (J7T81_05740)	murA	1105202..1106473 (-)	1272	WP_014608377.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J7T81_RS05765 (J7T81_05745)	-	1106543..1106779 (-)	237	WP_002946959.1	DUF1146 family protein	-
J7T81_RS05770 (J7T81_05750)	galE	1106967..1107980 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
J7T81_RS05775 (J7T81_05755)	-	1107995..1108450 (-)	456	WP_024009932.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=553165 J7T81_RS05750 WP_011681210.1 1104069..1104950(-) (endA) [Streptococcus thermophilus strain S24732]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=553165 J7T81_RS05750 WP_011681210.1 1104069..1104950(-) (endA) [Streptococcus thermophilus strain S24732]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTAGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594