Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   J5D21_RS00100 Genome accession   NZ_CP071982
Coordinates   14559..16922 (+) Length   787 a.a.
NCBI ID   WP_209611829.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5135     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9559..21922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D21_RS00070 (J5D21_00070) groES 9586..9942 (-) 357 WP_000671934.1 co-chaperone GroES -
  J5D21_RS00075 (J5D21_00075) dnaG 10220..11899 (+) 1680 WP_209611823.1 DNA primase -
  J5D21_RS00080 (J5D21_00080) - 11896..12948 (+) 1053 WP_209611825.1 MnmA/TRMU family protein -
  J5D21_RS00085 (J5D21_00085) - 13041..13868 (+) 828 WP_209611827.1 DUF5718 family protein -
  J5D21_RS00090 (J5D21_00090) comB2 14013..14294 (+) 282 WP_001272690.1 TrbC/VirB2 family protein Machinery gene
  J5D21_RS00095 (J5D21_00095) comB3 14294..14557 (+) 264 WP_000584948.1 hypothetical protein Machinery gene
  J5D21_RS00100 (J5D21_00100) comB4 14559..16922 (+) 2364 WP_209611829.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  J5D21_RS00110 (J5D21_00110) - 17231..18571 (+) 1341 WP_209612451.1 COG3014 family protein -
  J5D21_RS00115 (J5D21_00115) cheV1 18677..19642 (+) 966 WP_000785486.1 chemotaxis protein CheV1 -
  J5D21_RS00120 (J5D21_00120) nspC 19639..20856 (+) 1218 WP_209611831.1 carboxynorspermidine decarboxylase -
  J5D21_RS00125 (J5D21_00125) lpxE 20933..21505 (-) 573 WP_209611833.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90157.53 Da        Isoelectric Point: 7.9626

>NTDB_id=549665 J5D21_RS00100 WP_209611829.1 14559..16922(+) (comB4) [Helicobacter pylori strain MT5135]
MLEKFLGAIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVVRLVVKRRKIDYKQNIQSDSQYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETFKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQEGFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISSAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSSAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=549665 J5D21_RS00100 WP_209611829.1 14559..16922(+) (comB4) [Helicobacter pylori strain MT5135]
ATGCTAGAAAAGTTTTTAGGCGCTATCAAGCAAAAAGTTTCAAATTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCAAT
GAGTGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTGCTCACTAAAAACGAAAACTTAGTGGGAATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACTGAACGCCAAATGGCGTTGGAT
TCTTTGGAAAAGGTCGTGGTGCGCCTGGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAACATTCAATCTGATTCTCA
ATACTTGCAAGCGATCTTGAATCAATTTGAAAATAAAGAAGTGTATGAGAATCAGTATTTTTTGGTTTTAGAAAGCGCGC
ACTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCTCTCATGCATGCCAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTTAAAAGCTTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAACGGGTTTGATCTCCCTTTAAAGCCTCTAGTAGGAGGGTATTTGA
GCGATAGCTATATTGCTAGTTCTATCACTTTTGAAAAAGATTACTTCATTCAAGAGGGTTTTAACCAAAAAACCTATAAC
CGCTTGATTGGCATTAAGGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCTAATCTTGTTAAAAACGAGCTATTAGAATACCAAGAATTAGTCAAAACCAAACGATTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATCAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCTTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATCTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTCGATCTCGCCCCCTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTAGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGATTTTAGTTTGCTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAATTCCAGCGCTTTTTTAAACGTGATAAACCTAGATGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAGATCTTAGAAGAGTCTAGGAAAAACGACAGCGGCTTTTTGGTTTTTTTAGAC
GAATTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCCTTGCAAGACATTTACCAACTCAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAATTGAAACACAACTTCAATGTGCCTTTGAGCGAGACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGCTCTAACATGATTGACGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCAGATTCTAGTCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

96.95

100

0.97