Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SPYJRS4_RS07040 Genome accession   NZ_AP012335
Coordinates   1403554..1404336 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes JRS4     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1398554..1409336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYJRS4_RS07015 (SPYJRS4_1477) gatB 1398652..1400091 (-) 1440 WP_011184879.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  SPYJRS4_RS07020 (SPYJRS4_1478) gatA 1400091..1401557 (-) 1467 WP_011184880.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  SPYJRS4_RS07025 (SPYJRS4_1479) gatC 1401557..1401859 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SPYJRS4_RS07030 (SPYJRS4_1480) - 1402091..1402376 (-) 286 Protein_1355 putative PEP-binding protein -
  SPYJRS4_RS07035 (SPYJRS4_1482) - 1402853..1403407 (-) 555 WP_010922604.1 isochorismatase family cysteine hydrolase -
  SPYJRS4_RS07040 (SPYJRS4_1483) codY 1403554..1404336 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SPYJRS4_RS07045 (SPYJRS4_1484) - 1404554..1405768 (-) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  SPYJRS4_RS07050 (SPYJRS4_1485) - 1405999..1406451 (+) 453 WP_002983265.1 universal stress protein -
  SPYJRS4_RS07055 (SPYJRS4_1486) - 1406574..1407962 (-) 1389 WP_010922607.1 Cof-type HAD-IIB family hydrolase -
  SPYJRS4_RS07060 (SPYJRS4_1487) - 1408034..1408999 (+) 966 WP_011184885.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=54874 SPYJRS4_RS07040 WP_002983278.1 1403554..1404336(-) (codY) [Streptococcus pyogenes JRS4]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=54874 SPYJRS4_RS07040 WP_002983278.1 1403554..1404336(-) (codY) [Streptococcus pyogenes JRS4]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment