Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   CSB63_RS08970 Genome accession   NZ_CP089060
Coordinates   1692740..1693033 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain CH8     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1687740..1698033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSB63_RS08935 (CSB63_1880) - 1688143..1688586 (-) 444 WP_041829335.1 hypothetical protein -
  CSB63_RS08940 (CSB63_1881) - 1688660..1689079 (-) 420 WP_014727721.1 CPBP family intramembrane glutamic endopeptidase -
  CSB63_RS08945 (CSB63_1883) - 1689328..1689525 (-) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  CSB63_RS08950 (CSB63_1884) - 1689774..1690967 (-) 1194 WP_014608740.1 acetate kinase -
  CSB63_RS08955 (CSB63_1885) comGH 1691023..1691979 (-) 957 WP_011681684.1 class I SAM-dependent methyltransferase Machinery gene
  CSB63_RS08960 (CSB63_1886) comGG 1692024..1692341 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG Machinery gene
  CSB63_RS08965 (CSB63_1887) comGF 1692319..1692756 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  CSB63_RS08970 comGE 1692740..1693033 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  CSB63_RS08975 (CSB63_1889) comGD 1693005..1693433 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  CSB63_RS08980 (CSB63_1890) comGC 1693393..1693719 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  CSB63_RS08985 (CSB63_1891) comGB 1693716..1694816 (-) 1101 WP_134973504.1 competence type IV pilus assembly protein ComGB Machinery gene
  CSB63_RS08990 (CSB63_1892) - 1694698..1695390 (-) 693 Protein_1709 ATPase, T2SS/T4P/T4SS family -
  CSB63_RS08995 (CSB63_1893) - 1695448..1696800 (-) 1353 WP_134973005.1 IS66-like element short variant transposase -
  CSB63_RS09000 (CSB63_1894) - 1696754..1696960 (-) 207 WP_134973004.1 transposase -
  CSB63_RS09005 (CSB63_1895) tnpB 1697011..1697361 (-) 351 WP_014295152.1 IS66 family insertion sequence element accessory protein TnpB -
  CSB63_RS09010 (CSB63_1896) - 1697342..1697527 (-) 186 WP_134973003.1 hypothetical protein -
  CSB63_RS09015 (CSB63_1897) - 1697609..1697875 (-) 267 Protein_1714 hypothetical protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=548090 CSB63_RS08970 WP_011226625.1 1692740..1693033(-) (comGE) [Streptococcus thermophilus strain CH8]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=548090 CSB63_RS08970 WP_011226625.1 1692740..1693033(-) (comGE) [Streptococcus thermophilus strain CH8]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361