Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   SPYOHK_RS06905 Genome accession   NZ_AFRY01000001
Coordinates   449691..450473 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes HKU QMH11M0907901     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 444691..455473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYOHK_RS06925 (SPYOHK_02150) - 445028..445993 (-) 966 WP_002983258.1 asparaginase -
  SPYOHK_RS06920 (SPYOHK_02155) - 446065..447453 (+) 1389 WP_002988557.1 Cof-type HAD-IIB family hydrolase -
  SPYOHK_RS06915 (SPYOHK_02160) - 447576..448028 (-) 453 WP_002983265.1 universal stress protein -
  SPYOHK_RS06910 (SPYOHK_02165) - 448259..449473 (+) 1215 WP_002988558.1 pyridoxal phosphate-dependent aminotransferase -
  SPYOHK_RS06905 (SPYOHK_02170) codY 449691..450473 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  SPYOHK_RS06900 (SPYOHK_02175) - 450620..451174 (+) 555 WP_002988559.1 cysteine hydrolase family protein -
  SPYOHK_RS06895 (SPYOHK_02180) - 451713..451937 (+) 225 WP_002988560.1 putative PEP-binding protein -
  SPYOHK_RS06890 (SPYOHK_02185) gatC 452169..452471 (+) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  SPYOHK_RS06885 (SPYOHK_02190) gatA 452471..453937 (+) 1467 WP_002988562.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  SPYOHK_RS06880 (SPYOHK_02195) gatB 453937..455376 (+) 1440 WP_002988563.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=53969 SPYOHK_RS06905 WP_002983278.1 449691..450473(+) (codY) [Streptococcus pyogenes HKU QMH11M0907901]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=53969 SPYOHK_RS06905 WP_002983278.1 449691..450473(+) (codY) [Streptococcus pyogenes HKU QMH11M0907901]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment