Detailed information NTG0053823

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: SPB_RS06125
• Genome accession: NZ_AEUT02000001
• Coordinates: 1220308..1221090 (-)
• Length: 260 a.a.
• NCBI ID: WP_003103534.1
• Uniprot ID: A0ABN0IQT1
• Organism: Streptococcus parauberis NCFD 2020
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1215308..1226090

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPB_RS06090 (SPB_1260)	-	1215646..1216278 (-)	633	WP_003104563.1	helix-turn-helix transcriptional regulator	-
SPB_RS11515	-	1216460..1216642 (+)	183	Protein_1216	3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein	-
SPB_RS11255	-	1216629..1216987 (+)	359	Protein_1217	IS3 family transposase	-
SPB_RS06100 (SPB_1262)	-	1217040..1217339 (-)	300	WP_003105267.1	rhodanese-like domain-containing protein	-
SPB_RS06105 (SPB_1263)	-	1217332..1218987 (-)	1656	WP_003103950.1	FAD-dependent oxidoreductase	-
SPB_RS06110 (SPB_1264)	-	1219008..1219331 (-)	324	WP_003104545.1	rhodanese-like domain-containing protein	-
SPB_RS06115 (SPB_1265)	-	1219467..1219727 (+)	261	WP_003103711.1	metal-sensitive transcriptional regulator	-
SPB_RS06120 (SPB_1266)	-	1219758..1220306 (-)	549	WP_003102874.1	cysteine hydrolase family protein	-
SPB_RS06125 (SPB_1267)	codY	1220308..1221090 (-)	783	WP_003103534.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
SPB_RS06130 (SPB_1268)	-	1221270..1222484 (-)	1215	WP_003103131.1	pyridoxal phosphate-dependent aminotransferase	-
SPB_RS06135 (SPB_1269)	-	1222678..1223130 (+)	453	WP_003103948.1	universal stress protein	-
SPB_RS06140 (SPB_1270)	-	1223160..1224548 (-)	1389	WP_003105322.1	Cof-type HAD-IIB family hydrolase	-
SPB_RS06145 (SPB_1271)	-	1224620..1225582 (+)	963	WP_003106022.1	asparaginase	-

Sequence

Protein

• Length: 260 a.a.
• Molecular weight: 28818.86 Da
• Isoelectric Point: 4.3770

>NTDB_id=53823 SPB_RS06125 WP_003103534.1 1220308..1221090(-) (codY) [Streptococcus parauberis NCFD 2020]
MPNLLEKTRKITSILQRSVDSLDTELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNNDRVEEFFEAKQFPDSYV
KAASRVYDTEANLTVENELTIFPVESKDDFPEGLTTIAPIYGGGMRLGSLIIWRNDEQFDDDDLILVEISSTVVGIQLLN
LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEY

Nucleotide

• Length: 783 bp

>NTDB_id=53823 SPB_RS06125 WP_003103534.1 1220308..1221090(-) (codY) [Streptococcus parauberis NCFD 2020]
ATGCCAAATTTATTAGAAAAAACACGTAAAATTACGTCCATTCTACAGCGTTCCGTTGATAGTTTAGATACTGAACTACC
ATACAATACAATGGCATCTCGTTTAGCAGATATTATTGATTGTAATGCTTGTATTATTAATGGTGGTGGAACTCTATTGG
GTTATGCCATGAAATATAAAACAAATAATGACCGCGTTGAAGAGTTCTTTGAAGCGAAGCAATTTCCAGATTCATATGTT
AAAGCAGCAAGTCGTGTTTATGATACAGAAGCAAACTTAACTGTTGAAAACGAGTTAACAATCTTTCCAGTTGAATCTAA
AGATGACTTTCCAGAGGGATTGACAACAATTGCCCCAATTTATGGTGGCGGTATGCGATTGGGTTCATTAATTATTTGGC
GTAATGATGAACAATTTGATGATGATGATTTGATTTTGGTTGAAATTTCAAGTACTGTTGTAGGTATTCAATTACTTAAC
TTACAAACAGAAAACCTTGAAGAAACAATACGTAAACAAACTGCTGTAAATATGGCAATTAATACCCTATCTTATTCTGA
AATGAAAGCTGTCGCAGCTATTTTAGGTGAATTAGATGGTAACGAAGGACGTTTAACAGCATCAGTAATTGCTGATCGTA
TTGGAATTACGCGTTCTGTTATTGTTAATGCCTTACGTAAGCTTGAAAGTGCTGGGATTATTGAAAGTCGCTCACTTGGT
ATGAAGGGAACTTATTTAAAAGTTATTAATGAAGGTATCTTTGATAAACTAAAGGAATATTAA

Domains

Predicted by InterProScan.

• CodY helix-turn-helix domain (HTH_CodY) (202-260)

• CodY GAF-like domain (CodY) (3-182)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	67.704	98.846	0.669
codY	Bacillus subtilis subsp. subtilis str. 168	54.251	95	0.515