Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   I6K87_RS04335 Genome accession   NZ_CP069892
Coordinates   872365..873210 (-) Length   281 a.a.
NCBI ID   WP_049533575.1    Uniprot ID   A0A1F0NJS4
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 867365..878210
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS04325 (I6K87_04325) - 868560..870329 (-) 1770 WP_204982809.1 ABC transporter ATP-binding protein -
  I6K87_RS04330 (I6K87_04330) - 870339..872075 (-) 1737 WP_204982810.1 ABC transporter ATP-binding protein -
  I6K87_RS04335 (I6K87_04335) endA 872365..873210 (-) 846 WP_049533575.1 DNA/RNA non-specific endonuclease Machinery gene
  I6K87_RS04340 (I6K87_04340) - 873309..873485 (-) 177 WP_003028073.1 DNA-directed RNA polymerase subunit beta -
  I6K87_RS04345 (I6K87_04345) murA 873478..874758 (-) 1281 WP_003028071.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  I6K87_RS04350 (I6K87_04350) - 874797..875027 (-) 231 WP_018543445.1 DUF1146 family protein -
  I6K87_RS04355 (I6K87_04355) - 875132..875551 (-) 420 WP_003025266.1 F0F1 ATP synthase subunit epsilon -
  I6K87_RS04360 (I6K87_04360) atpD 875562..876968 (-) 1407 WP_003025268.1 F0F1 ATP synthase subunit beta -
  I6K87_RS04365 (I6K87_04365) - 877003..877881 (-) 879 WP_003028065.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30618.25 Da        Isoelectric Point: 10.4350

>NTDB_id=537241 I6K87_RS04335 WP_049533575.1 872365..873210(-) (endA) [Streptococcus anginosus strain FDAARGOS_1357]
MARKKSNQKVAQSVAGLVIALVLALGGYSFSNHHGSTKPSDSTAINRSIRTNHAAPSQELAQSVLTESVKRQLKGKIEWN
GAGAFTINENKTTLDAKVASVPYADNKTKLVRGQTVPTVANALLSKTTRQYRSREETGNGSTTWTPAGWHQVKHLSGEYN
HAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANTSHSTGQNFYETKVRKALDNNKRVRYRVTLIYANEQDLV
PVGSHIEAKSSDSSLEMNVFVPNVQTGLRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=537241 I6K87_RS04335 WP_049533575.1 872365..873210(-) (endA) [Streptococcus anginosus strain FDAARGOS_1357]
ATGGCGAGAAAGAAATCCAATCAGAAAGTAGCACAAAGTGTAGCTGGTTTGGTTATAGCACTGGTTCTTGCGCTGGGAGG
TTATTCTTTTAGCAATCATCATGGTAGTACGAAGCCTTCTGACAGCACTGCTATTAATCGAAGTATTCGGACGAATCATG
CAGCACCCAGTCAAGAATTAGCACAGAGTGTTTTGACAGAGTCCGTTAAACGGCAACTCAAAGGAAAGATTGAATGGAAT
GGGGCAGGAGCCTTCACAATCAATGAAAATAAAACAACATTGGATGCTAAAGTTGCAAGCGTTCCTTATGCGGATAATAA
GACTAAACTCGTCCGAGGTCAGACCGTTCCGACGGTTGCAAATGCTCTTTTATCCAAAACAACTCGCCAATATAGAAGTC
GTGAAGAAACAGGAAATGGCTCCACGACTTGGACGCCTGCTGGTTGGCATCAAGTCAAGCATTTATCAGGTGAATACAAC
CATGCAGTTGACCGAGGACATTTGTTGGGTTATGCTTTGATTGGTAACTTGAAAGGGTTTGATGCTTCGACCAGTAACCC
GAAAAATATAGCTGTGCAAACAGCTTGGGCTAATCAAGCAAATACTAGTCATTCTACGGGTCAAAATTTCTATGAAACAA
AGGTTCGCAAGGCACTAGACAATAATAAACGAGTTCGGTATCGGGTGACTTTGATTTATGCCAATGAACAGGATTTAGTG
CCAGTTGGTTCGCATATTGAAGCTAAATCAAGCGATAGTAGCTTGGAAATGAATGTCTTTGTTCCCAACGTACAGACAGG
ACTTCGGCTAAATTATCAAACAGGAGAAGTGACCGTTACCAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(83-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1F0NJS4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

76.549

80.427

0.616
  endA Streptococcus pneumoniae D39

76.549

80.427

0.616
  endA Streptococcus pneumoniae R6

76.549

80.427

0.616
  endA Streptococcus pneumoniae TIGR4

76.549

80.427

0.616