Detailed information NTG0536700

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1099_RS09400
• Genome accession: NZ_CP069796
• Coordinates: 1949930..1950586 (+)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 6 str. Femo
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1944930..1955586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1099_RS09355 (D1099_09335)	rplP	1945001..1945411 (-)	411	WP_005599294.1	50S ribosomal protein L16	-
D1099_RS09360 (D1099_09340)	rpsC	1945425..1946132 (-)	708	WP_005599293.1	30S ribosomal protein S3	-
D1099_RS09365 (D1099_09345)	rplV	1946151..1946483 (-)	333	WP_005609200.1	50S ribosomal protein L22	-
D1099_RS09370 (D1099_09350)	rpsS	1946494..1946769 (-)	276	WP_005539416.1	30S ribosomal protein S19	-
D1099_RS09375 (D1099_09355)	rplB	1946797..1947618 (-)	822	WP_005599291.1	50S ribosomal protein L2	-
D1099_RS09380 (D1099_09360)	rplW	1947639..1947944 (-)	306	WP_005599290.1	50S ribosomal protein L23	-
D1099_RS09385 (D1099_09365)	rplD	1947941..1948543 (-)	603	WP_005599282.1	50S ribosomal protein L4	-
D1099_RS09390 (D1099_09370)	rplC	1948559..1949185 (-)	627	WP_005599280.1	50S ribosomal protein L3	-
D1099_RS09395 (D1099_09375)	rpsJ	1949211..1949522 (-)	312	WP_001181005.1	30S ribosomal protein S10	-
D1099_RS09400 (D1099_09380)	sxy/tfoX	1949930..1950586 (+)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1099_RS09405 (D1099_09385)	fumC	1950741..1952135 (+)	1395	WP_005605803.1	class II fumarate hydratase	-
D1099_RS09410 (D1099_09390)	nagA	1952285..1953430 (-)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1099_RS09415 (D1099_09395)	nagB	1953482..1954285 (-)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
D1099_RS09420 (D1099_09400)	nanA	1954335..1955213 (-)	879	WP_005599265.1	N-acetylneuraminate lyase	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=536700 D1099_RS09400 WP_005609196.1 1949930..1950586(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 6 str. Femo]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=536700 D1099_RS09400 WP_005609196.1 1949930..1950586(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 6 str. Femo]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376