Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   K8227_RS01220 Genome accession   NZ_CP082948
Coordinates   226875..229208 (+) Length   777 a.a.
NCBI ID   WP_012775425.1    Uniprot ID   A0A0H3MT16
Organism   Streptococcus suis strain SZ1908     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 221875..234208
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8227_RS01200 (K8227_01200) treP 222869..224863 (-) 1995 WP_011921815.1 PTS system trehalose-specific EIIBC component -
  K8227_RS01205 (K8227_01205) treR 225097..225810 (+) 714 WP_012774930.1 trehalose operon repressor Regulator
  K8227_RS01210 (K8227_01210) - 225868..226179 (+) 312 WP_002935948.1 hypothetical protein -
  K8227_RS01215 (K8227_01215) - 226176..226724 (+) 549 WP_002935945.1 CvpA family protein -
  K8227_RS01220 (K8227_01220) mutS/mutS2 226875..229208 (+) 2334 WP_012775425.1 endonuclease MutS2 Machinery gene
  K8227_RS01225 (K8227_01225) - 229232..229885 (+) 654 WP_011921818.1 GNAT family N-acetyltransferase -
  K8227_RS01230 (K8227_01230) trxA 230092..230406 (+) 315 WP_012775426.1 thioredoxin -
  K8227_RS01235 (K8227_01235) - 230596..231717 (+) 1122 WP_015445098.1 IS110 family transposase -
  K8227_RS10525 - 232241..232291 (-) 51 WP_353735889.1 hypothetical protein -
  K8227_RS01240 (K8227_01240) - 232281..233810 (+) 1530 WP_012774931.1 AMP-binding protein -

Sequence

Protein


Download         Length: 777 a.a.        Molecular weight: 87550.34 Da        Isoelectric Point: 6.8323

>NTDB_id=530902 K8227_RS01220 WP_012775425.1 226875..229208(+) (mutS/mutS2) [Streptococcus suis strain SZ1908]
MNNKIIETLEFHKVRQKIEPYLLTEQGFEELRQLEPMVEVHRIQQAFDELTDIAQIFVENPYFSLAATSDIGPAMRRLEL
DTDLNIAELLAVKKVLEVSKSLLDFYGNLENVSLSQLDKLFEKIELFPHLQGSLQSINDAGFVEDFASEKLARIRRKIRE
AEDQVRQVMQDILKTKGDMLSDSILASRNGRNVLPVKNTYRNKIAGVVHDISASGSTVYIEPRAVVTLNEEISHLRAEER
HELNRILQELSDMLRPHGGVIRNNAWLIGHIDFVRAKHLFARDHQAVVPKLSEKQDIALLNVRHPLIAKPVPNDLYFGSQ
LTAIVITGPNTGGKTIMLKTLGLTHLMAQSGLPILADKGSRVAIFKEIFADIGDEQSIEQSLSTFSSHMTHTVEILRAAD
QDSLILFDELGAGTDPQEGASLAMAILDDLRLRGIKTMATTHYPELKAYGIETSGIENASMEFDSNSLRPTYKFMQGVPG
RSNAFEIARRLGLSDIIIQSAQSWTDTDSDVNRIIEKLESQTVESRQRLDKIRDVEQENYKMNRALRKLYDELNRERENE
LNKARLEAKEIVDMALAESEDILKNLHAAASLKPHQIIEAKAELKKLAPEVVDLSKNKVLKKAKIKREAKVGDDIIVTAY
GQRGTLTNQLKDGRWEAQVGLIKMTLAKDEFELVKAEKAEQPKKRQVHTVKRANVRGPKARLDLRGKRYEEAMMELDEFI
DQALLNNLAQVDIVHGIGTGVIREGVTKYLRRNKQIKEFGYAPQNAGGSGCTIVTFK

Nucleotide


Download         Length: 2334 bp        

>NTDB_id=530902 K8227_RS01220 WP_012775425.1 226875..229208(+) (mutS/mutS2) [Streptococcus suis strain SZ1908]
ATGAATAATAAAATTATTGAAACCCTTGAATTTCACAAGGTAAGACAAAAAATTGAGCCCTATCTCTTGACGGAACAGGG
CTTTGAAGAATTACGACAGTTGGAGCCCATGGTGGAAGTCCATCGTATCCAACAGGCCTTCGACGAGTTGACAGACATAG
CGCAGATTTTTGTGGAAAATCCCTATTTCAGTCTGGCTGCTACTAGTGACATCGGTCCAGCCATGCGTCGTTTGGAATTG
GATACAGACCTCAATATCGCTGAATTATTAGCTGTTAAAAAGGTCTTGGAAGTTTCTAAATCTCTCTTGGATTTTTATGG
AAATCTGGAAAATGTCAGTCTTAGCCAGTTGGATAAACTCTTTGAGAAGATTGAGCTTTTTCCACATTTACAGGGCTCCC
TCCAGTCCATCAATGATGCTGGTTTTGTAGAGGATTTTGCCTCAGAAAAGCTGGCTCGTATTCGAAGAAAAATCCGTGAA
GCTGAAGATCAAGTTCGTCAGGTCATGCAGGATATTTTGAAGACCAAGGGCGACATGCTGTCCGATAGCATTTTGGCAAG
CCGTAATGGACGCAATGTCCTTCCTGTTAAAAATACCTATCGCAATAAGATTGCAGGGGTTGTCCATGACATTTCAGCTT
CGGGTTCGACCGTTTATATTGAGCCGCGGGCAGTGGTGACCTTGAACGAAGAAATCAGTCACCTACGTGCAGAAGAACGC
CATGAGCTCAACCGTATCTTGCAGGAATTGTCGGATATGCTCCGTCCGCATGGTGGCGTGATTCGTAACAATGCCTGGCT
TATCGGACATATTGATTTCGTCCGTGCTAAGCATCTCTTTGCGCGTGATCATCAAGCAGTTGTACCCAAACTATCTGAGA
AGCAGGATATTGCCCTTCTCAACGTTCGGCATCCGCTCATTGCTAAGCCTGTACCAAATGACCTTTATTTCGGTAGTCAG
TTGACGGCTATCGTGATAACAGGTCCCAACACAGGTGGTAAGACCATCATGCTTAAGACCTTGGGATTGACCCATCTGAT
GGCCCAGTCTGGTTTGCCTATCTTGGCTGATAAGGGCAGTCGGGTAGCTATCTTCAAAGAAATTTTTGCGGATATTGGGG
ATGAACAGTCGATTGAGCAGAGTTTATCAACCTTCTCCAGTCACATGACCCACACGGTGGAAATTTTAAGAGCAGCTGAT
CAAGATTCTCTCATTCTCTTTGACGAGTTGGGAGCTGGGACAGATCCGCAGGAGGGTGCGTCTTTGGCTATGGCTATTTT
GGATGACCTTCGTCTGCGGGGGATCAAGACCATGGCGACCACCCACTACCCTGAGCTTAAGGCCTACGGGATAGAAACCT
CTGGTATTGAAAATGCCAGCATGGAGTTTGATAGCAATAGCCTGCGTCCGACCTATAAGTTTATGCAGGGTGTTCCTGGT
CGCTCCAATGCCTTTGAAATTGCCCGCCGTCTTGGTCTATCTGATATTATTATCCAGTCAGCCCAATCTTGGACGGATAC
AGATAGCGATGTGAACCGCATTATCGAGAAATTGGAAAGTCAGACGGTTGAAAGTCGTCAACGTCTGGATAAGATTCGTG
ATGTGGAGCAAGAAAATTACAAGATGAACCGAGCCCTCCGCAAGCTCTATGACGAGCTCAATCGTGAGCGGGAAAATGAG
CTCAACAAGGCACGCTTGGAAGCCAAGGAAATTGTAGATATGGCATTGGCAGAAAGCGAGGATATTCTCAAAAATCTCCA
TGCTGCAGCTAGTCTTAAGCCCCATCAGATTATCGAAGCCAAGGCAGAGCTGAAAAAGTTGGCGCCTGAAGTGGTGGATC
TGTCTAAAAACAAGGTTCTGAAGAAAGCTAAAATTAAGAGGGAAGCCAAGGTGGGCGATGACATTATCGTTACAGCTTAT
GGACAACGCGGGACCTTGACCAATCAGCTCAAGGACGGGCGTTGGGAAGCTCAGGTTGGCTTGATTAAGATGACCTTGGC
TAAAGATGAGTTTGAGTTAGTCAAGGCGGAAAAGGCAGAGCAGCCTAAGAAACGCCAGGTTCACACAGTCAAACGTGCCA
ATGTACGAGGACCAAAAGCCCGCTTAGATCTCCGTGGCAAACGTTACGAAGAGGCTATGATGGAGCTGGATGAATTTATC
GACCAGGCCCTTCTCAATAACCTAGCCCAAGTCGATATTGTCCACGGTATTGGTACTGGAGTCATCCGAGAAGGGGTGAC
CAAGTACCTACGCCGCAACAAGCAGATCAAGGAGTTCGGCTATGCCCCACAAAATGCAGGTGGATCAGGCTGTACTATTG
TGACGTTTAAATAG

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(631-670)

MutS domain V (MutS_V)

(324-504)

Smr domain (Smr)

(702-777)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MT16

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.52

100

0.403