Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   I6J12_RS02175 Genome accession   NZ_CP068060
Coordinates   454203..455048 (+) Length   281 a.a.
NCBI ID   WP_020999531.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 449203..460048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS02145 (I6J12_02145) - 449530..450408 (+) 879 WP_003025271.1 F0F1 ATP synthase subunit gamma -
  I6J12_RS02150 (I6J12_02150) atpD 450443..451849 (+) 1407 WP_003037320.1 F0F1 ATP synthase subunit beta -
  I6J12_RS02155 (I6J12_02155) - 451860..452279 (+) 420 WP_003028068.1 F0F1 ATP synthase subunit epsilon -
  I6J12_RS02160 (I6J12_02160) - 452384..452614 (+) 231 WP_018543445.1 DUF1146 family protein -
  I6J12_RS02165 (I6J12_02165) murA 452653..453933 (+) 1281 WP_003037494.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  I6J12_RS02170 (I6J12_02170) - 453926..454102 (+) 177 WP_003037331.1 DNA-directed RNA polymerase subunit beta -
  I6J12_RS02175 (I6J12_02175) endA 454203..455048 (+) 846 WP_020999531.1 DNA/RNA non-specific endonuclease Machinery gene
  I6J12_RS02180 (I6J12_02180) - 455340..457076 (+) 1737 WP_003037228.1 ABC transporter ATP-binding protein -
  I6J12_RS02185 (I6J12_02185) - 457086..458855 (+) 1770 WP_003037521.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30624.28 Da        Isoelectric Point: 10.4147

>NTDB_id=526790 I6J12_RS02175 WP_020999531.1 454203..455048(+) (endA) [Streptococcus anginosus strain FDAARGOS_1155]
MARKKSNQKVTQSVAGLVIALVLVLGGYSFSNHHSSTKPSDSTAINRSIRTNHAAPSQELAQSVLTESVKRQLKGKIEWN
GAGAFTINENQTTLDAKVASVPYADNKTKLVRGQTVPTVANALLSKATRQYKNREETGNGSTTWTPAGWHQVKHLSGEYN
HAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANTGHSTGQNFYETKVRKALDKNKRVRYRVTLIYANEQDLV
PVGSHIEGKSNDGSLEINVFVPNVQTGLRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=526790 I6J12_RS02175 WP_020999531.1 454203..455048(+) (endA) [Streptococcus anginosus strain FDAARGOS_1155]
ATGGCGAGAAAGAAATCCAACCAGAAAGTAACACAAAGTGTAGCTGGTCTGGTTATAGCACTGGTTCTTGTGCTAGGAGG
TTATTCTTTTAGCAATCATCATAGTAGTACGAAGCCTTCTGACAGCACTGCTATTAATCGAAGTATTCGGACGAATCATG
CAGCACCCAGTCAAGAATTAGCGCAGAGTGTTTTGACAGAATCCGTCAAGCGGCAGCTTAAAGGAAAGATCGAATGGAAT
GGAGCGGGAGCTTTCACAATCAACGAAAATCAAACAACATTGGATGCCAAAGTCGCAAGCGTTCCTTACGCGGATAATAA
GACCAAGCTCGTCCGGGGTCAGACTGTTCCGACTGTAGCCAATGCTCTTTTATCCAAAGCCACTCGTCAGTATAAGAATC
GTGAGGAGACAGGAAATGGCTCCACGACTTGGACACCTGCTGGTTGGCATCAGGTGAAGCATTTATCAGGTGAATATAAT
CATGCGGTTGACCGTGGGCATTTGTTGGGTTATGCTTTGATTGGCAACTTGAAAGGCTTTGATGCTTCGACCAGCAACCC
GAAAAACATCGCTGTGCAAACAGCTTGGGCTAATCAAGCCAATACTGGTCATTCTACGGGTCAAAATTTTTATGAAACAA
AGGTCCGCAAGGCACTAGACAAAAATAAACGAGTTCGGTATCGGGTGACTTTGATTTATGCCAATGAACAGGATTTGGTG
CCGGTTGGTTCGCATATTGAAGGCAAATCTAATGACGGCAGTCTGGAAATAAATGTCTTTGTTCCCAACGTACAGACAGG
ACTTCGGCTAAATTATCAAACAGGAGAAGTGACTGTTACCAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(83-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

76.991

80.427

0.619
  endA Streptococcus pneumoniae D39

76.991

80.427

0.619
  endA Streptococcus pneumoniae R6

76.991

80.427

0.619
  endA Streptococcus pneumoniae TIGR4

76.991

80.427

0.619