Detailed information NTG0522132

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JGY88_RS05005
• Genome accession: NZ_CP066721
• Coordinates: 1067744..1068787 (+)
• Length: 347 a.a.
• NCBI ID: WP_042362410.1
• Uniprot ID: A0A5R9B245
• Organism: Staphylococcus xylosus strain 2.1523
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1062744..1073787

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JGY88_RS04980 (JGY88_04945)	-	1063699..1064421 (+)	723	WP_107537702.1	type 1 glutamine amidotransferase	-
JGY88_RS04985 (JGY88_04950)	-	1064623..1065609 (-)	987	WP_042362407.1	aromatic acid exporter family protein	-
JGY88_RS04990 (JGY88_04955)	map	1065786..1066538 (+)	753	WP_039069016.1	type I methionyl aminopeptidase	-
JGY88_RS04995 (JGY88_04960)	-	1066643..1067029 (+)	387	WP_042362408.1	hypothetical protein	-
JGY88_RS05000 (JGY88_04965)	liaF	1067046..1067747 (+)	702	WP_042362409.1	cell wall-active antibiotics response protein LiaF	-
JGY88_RS05005 (JGY88_04970)	vraS	1067744..1068787 (+)	1044	WP_042362410.1	sensor histidine kinase	Regulator
JGY88_RS05010 (JGY88_04975)	vraR	1068777..1069406 (+)	630	WP_017723494.1	response regulator transcription factor	Regulator
JGY88_RS05015 (JGY88_04980)	-	1069671..1070816 (-)	1146	WP_225486845.1	YihY/virulence factor BrkB family protein	-
JGY88_RS05020 (JGY88_04985)	-	1071172..1071456 (-)	285	WP_225486846.1	YtxH domain-containing protein	-
JGY88_RS05025 (JGY88_04990)	-	1071463..1071927 (-)	465	WP_029378983.1	low molecular weight protein-tyrosine-phosphatase	-
JGY88_RS05030 (JGY88_04995)	-	1072062..1072265 (+)	204	WP_225486847.1	DUF1128 family protein	-
JGY88_RS05035 (JGY88_05000)	-	1072283..1073521 (+)	1239	WP_225486848.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40037.55 Da
• Isoelectric Point: 6.4215

>NTDB_id=522132 JGY88_RS05005 WP_042362410.1 1067744..1068787(+) (vraS) [Staphylococcus xylosus strain 2.1523]
MNHYIRAIGSMLILVYSTFFAIFFIDKVFVNVMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNRDDYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSYAD

Nucleotide

• Length: 1044 bp

>NTDB_id=522132 JGY88_RS05005 WP_042362410.1 1067744..1068787(+) (vraS) [Staphylococcus xylosus strain 2.1523]
ATGAATCACTACATTAGAGCAATAGGTTCGATGTTGATATTAGTTTATAGTACATTTTTTGCTATATTTTTTATTGATAA
AGTATTTGTTAACGTAATGTACTTTCAAGGTATGTTTTATACCCAAATATTTGGTATACCCGTCTTATTATTTTTAAATT
TAATGGTTATTTTGCTCTGTATTATTGTAGGTTCTGTATTAGCTTATAAAATAAACCAACAAAATCATTGGTTAAAAGAC
CAAATAGAAAGATCAATAGAAGGGCAAACTGTAGGTATAAATGATCAAAATATAGAATTGTATAACGAAACCATTGAGTT
ATATCAAACGTTAGTCCCTTTAAATCAAGAAGTACATAAATTAAGGATGAAAACGCAAAATTTAACTAATGAATCATATA
ATATTAATGATGTAAAAGTGAAAAAAATTATTGAAGATGAACGACAAAGGCTCGCACGTGAATTACATGATTCAGTGAGT
CAACAGTTGTTCGCAGCTAGCATGATGTTATCAGCAATAAAAGAAACAAAATTAGAAGCACCATTAGATCAGCAAATTCC
GGTACTAGAGAAAATGATTCAAGATTCTCAGCTAGAAATGAGAGCTTTATTACTACATTTAAGACCTATAGGCTTGAAAG
ATAAATCACTTGGTGAAGGTATTAAAGATTTAGTTGTAGATCTACAGAAAAAAGTACCGATGAAAGTTATACATGATATA
GAAGAATTTAAAGTACCTAAAGGTATTGAAGATCATTTATTTAGAATCACACAAGAAGCTATATCGAATACATTAAGGCA
TTCAAAAGGAACTAAAGTAACTATAGAGTTATTTAATAGGGATGATTATTTATTATTGAGAATACAAGATAATGGTAAAG
GCTTTAATGTTGATGATAAAGTAGAACAAAGTTATGGCTTAAAAAATATGCGTGAGCGTGCACTTGAGATTGGTGCAACG
TTTCATATTGTGTCACTACCTGATGCAGGTACCAGAATTGAAGTTAAAGCCCCATTGAATAAGGAGGATTCATATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A5R9B245

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.473	100	0.885