Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   HLV54_RS06005 Genome accession   NZ_CP080770
Coordinates   1257001..1257774 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain HL23187     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1252001..1262774
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HLV54_RS05985 (HLV54_001197) trmFO 1252344..1253651 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  HLV54_RS05990 (HLV54_001198) xerC 1254069..1254965 (+) 897 WP_001015609.1 tyrosine recombinase XerC -
  HLV54_RS05995 (HLV54_001199) hslV 1254962..1255507 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  HLV54_RS06000 (HLV54_001200) hslU 1255573..1256976 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  HLV54_RS06005 (HLV54_001201) codY 1257001..1257774 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  HLV54_RS06010 (HLV54_001202) - 1257825..1257917 (+) 93 WP_031788481.1 hypothetical protein -
  HLV54_RS06015 (HLV54_001203) rpsB 1258116..1258883 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  HLV54_RS06020 (HLV54_001204) - 1258917..1259030 (+) 114 WP_031845108.1 hypothetical protein -
  HLV54_RS06025 (HLV54_001205) tsf 1259065..1259946 (+) 882 WP_000201386.1 translation elongation factor Ts -
  HLV54_RS06030 (HLV54_001206) pyrH 1260083..1260805 (+) 723 WP_000057330.1 UMP kinase -
  HLV54_RS06035 (HLV54_001207) frr 1260824..1261378 (+) 555 WP_001280006.1 ribosome recycling factor -
  HLV54_RS06040 (HLV54_001208) - 1261751..1262521 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=521373 HLV54_RS06005 WP_000055337.1 1257001..1257774(+) (codY) [Staphylococcus aureus strain HL23187]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=521373 HLV54_RS06005 WP_000055337.1 1257001..1257774(+) (codY) [Staphylococcus aureus strain HL23187]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428