Detailed information NTG0519147

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: IGS65_RS07600
• Genome accession: NZ_CP066294
• Coordinates: 1536760..1537968 (+)
• Length: 402 a.a.
• NCBI ID: WP_192072444.1
• Uniprot ID: A0AAX1K1I7
• Organism: Streptococcus mutans strain 27-3
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1531760..1542968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGS65_RS07590 (IGS65_007590)	-	1535068..1535730 (-)	663	WP_002262652.1	YoaK family protein	-
IGS65_RS07595 (IGS65_007595)	rlmH	1536075..1536554 (-)	480	WP_002299259.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
IGS65_RS07600 (IGS65_007600)	htrA	1536760..1537968 (+)	1209	WP_192072444.1	trypsin-like peptidase domain-containing protein	Regulator
IGS65_RS07605 (IGS65_007605)	spo0J	1538443..1539216 (+)	774	WP_192072445.1	ParB/RepB/Spo0J family partition protein	Regulator
IGS65_RS07610 (IGS65_007610)	dnaA	1539418..1540776 (+)	1359	WP_002262648.1	chromosomal replication initiator protein DnaA	-
IGS65_RS07615 (IGS65_007615)	dnaN	1540932..1542068 (+)	1137	WP_168750858.1	DNA polymerase III subunit beta	-
IGS65_RS07620 (IGS65_007620)	-	1542346..1542537 (+)	192	WP_002262646.1	DUF951 domain-containing protein	-

Sequence

Protein

• Length: 402 a.a.
• Molecular weight: 43085.57 Da
• Isoelectric Point: 8.8092

>NTDB_id=519147 IGS65_RS07600 WP_192072444.1 1536760..1537968(+) (htrA) [Streptococcus mutans strain 27-3]
MNNTKSHPFLKWFIPFLVIFLTFILGVISTLTFNWITGNKSFSNNGKTTVSNVIYDTKSNTTKAVKNVKNTVVSVINYQK
TDNSYYNYDSGSQEKNKSEDGLGVYGEGSGVIYKKDGDSAYLVTNNHVVKDAEKLEIMMANGKKVVGKLVGSDTYSDLAV
IKISSKYVTTVAEFANSDKIKVGEPAIAIGSPLGSDYANSVTEGIVSSLSRTVTSQNENGETISTNAIQTDAAINPGNSG
GALINIKGQVIGINSSKIASSNNSNSGVAVEGMGFAIPSNDVVSIINQLEENGEVVRPALGISMANLSEASTSGRDTLKI
PSDITSGIVVLSTQSGMPADGKLKKYDVITEIDGKKVASISDLQSILYKHKKGDKIKLTFYREKDKQTVEIQLTKTSQDL
NH

Nucleotide

• Length: 1209 bp

>NTDB_id=519147 IGS65_RS07600 WP_192072444.1 1536760..1537968(+) (htrA) [Streptococcus mutans strain 27-3]
GTGAATAATACGAAATCTCACCCTTTTTTAAAATGGTTTATACCTTTTTTAGTTATTTTTTTAACTTTTATTTTAGGGGT
CATATCAACACTTACCTTTAATTGGATAACTGGTAACAAATCGTTCTCTAACAATGGAAAAACAACTGTTAGTAATGTCA
TTTATGATACCAAATCTAACACTACCAAGGCTGTTAAAAATGTCAAAAATACAGTTGTATCTGTCATCAATTATCAAAAA
ACAGATAATAGTTATTACAATTATGACAGCGGTTCTCAAGAAAAAAATAAATCAGAGGATGGTCTAGGAGTCTACGGTGA
AGGTTCTGGTGTTATCTACAAAAAAGATGGCGATAGTGCTTATTTAGTCACAAACAATCATGTCGTTAAAGATGCAGAAA
AGTTAGAAATCATGATGGCTAATGGTAAAAAAGTTGTCGGTAAATTAGTAGGTTCTGATACTTATTCTGATCTGGCTGTT
ATTAAAATTTCTTCTAAGTATGTTACGACAGTTGCTGAATTTGCTAATTCGGATAAAATAAAAGTTGGAGAACCAGCAAT
CGCTATTGGTAGCCCTTTAGGCAGTGATTATGCTAATTCTGTAACAGAAGGAATTGTTTCAAGTCTCAGTCGTACAGTAA
CTTCACAAAATGAAAATGGCGAAACAATTTCAACTAATGCTATTCAAACAGACGCAGCTATTAACCCTGGTAATTCTGGT
GGCGCTTTAATTAATATCAAAGGACAAGTTATTGGTATCAATTCAAGTAAAATTGCATCAAGTAATAACTCAAATAGTGG
CGTTGCTGTTGAAGGAATGGGCTTTGCAATTCCTTCAAACGATGTTGTCTCTATTATTAATCAATTAGAAGAAAATGGTG
AAGTTGTTAGACCCGCTCTTGGTATTTCAATGGCTAATCTTAGTGAAGCTTCAACAAGTGGAAGAGATACTTTAAAAATA
CCAAGTGATATCACAAGCGGTATTGTTGTTCTTTCAACACAAAGTGGTATGCCAGCAGATGGGAAGCTGAAGAAATATGA
TGTCATTACAGAAATTGATGGGAAGAAGGTAGCGTCTATCAGCGATCTTCAAAGTATTCTTTACAAACACAAAAAGGGAG
ATAAAATTAAACTCACTTTCTATCGCGAAAAAGATAAACAAACAGTTGAGATCCAATTAACTAAAACAAGTCAAGATTTG
AATCATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

• Peptidase family M50 (Peptidase_M50) (223-398)

• PDZ domain (PDZ_2) (298-393)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	99.751	100	0.998
htrA	Streptococcus gordonii str. Challis substr. CH1	55.89	99.254	0.555
htrA	Streptococcus mitis NCTC 12261	54.43	98.259	0.535
htrA	Streptococcus pneumoniae Rx1	54.061	98.01	0.53
htrA	Streptococcus pneumoniae D39	54.061	98.01	0.53
htrA	Streptococcus pneumoniae R6	54.061	98.01	0.53
htrA	Streptococcus pneumoniae TIGR4	54.061	98.01	0.53