Detailed information NTG0519106

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: IGS65_RS01095
• Genome accession: NZ_CP066294
• Coordinates: 197857..198738 (+)
• Length: 293 a.a.
• NCBI ID: WP_002288136.1
• Uniprot ID: A0AAX1K343
• Organism: Streptococcus mutans strain 27-3
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 192857..203738

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGS65_RS01065 (IGS65_001065)	-	193040..193918 (+)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-
IGS65_RS01070 (IGS65_001070)	atpD	193944..195350 (+)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
IGS65_RS01075 (IGS65_001075)	-	195364..195780 (+)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
IGS65_RS01080 (IGS65_001080)	-	196054..196287 (+)	234	WP_002285829.1	DUF1146 family protein	-
IGS65_RS01085 (IGS65_001085)	murA	196353..197624 (+)	1272	WP_002262937.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
IGS65_RS01090 (IGS65_001090)	-	197627..197815 (+)	189	WP_002264826.1	DNA-directed RNA polymerase subunit beta	-
IGS65_RS01095 (IGS65_001095)	endA	197857..198738 (+)	882	WP_002288136.1	DNA/RNA non-specific endonuclease	Machinery gene
IGS65_RS01100 (IGS65_001100)	-	198806..199456 (-)	651	WP_002262934.1	amino acid ABC transporter permease	-
IGS65_RS01105 (IGS65_001105)	-	199471..200175 (-)	705	WP_002262933.1	amino acid ABC transporter permease	-
IGS65_RS01110 (IGS65_001110)	-	200193..201005 (-)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
IGS65_RS01115 (IGS65_001115)	-	201002..201784 (-)	783	WP_192072331.1	amino acid ABC transporter ATP-binding protein	-
IGS65_RS01120 (IGS65_001120)	vicR	202137..202844 (+)	708	WP_002262930.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32130.76 Da
• Isoelectric Point: 9.6655

>NTDB_id=519106 IGS65_RS01095 WP_002288136.1 197857..198738(+) (endA) [Streptococcus mutans strain 27-3]
MTRKTNKSKRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYASNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=519106 IGS65_RS01095 WP_002288136.1 197857..198738(+) (endA) [Streptococcus mutans strain 27-3]
ATGACTAGAAAAACGAACAAGTCTAAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAGTAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCGA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.103	79.863	0.512
endA	Streptococcus pneumoniae D39	64.103	79.863	0.512
endA	Streptococcus pneumoniae R6	64.103	79.863	0.512
endA	Streptococcus pneumoniae TIGR4	64.103	79.863	0.512