Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SCIM_RS06100 Genome accession   NC_018073
Coordinates   1255721..1256566 (-) Length   281 a.a.
NCBI ID   WP_003076919.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1250721..1261566
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS06090 (SCIM_1098) - 1252052..1253821 (-) 1770 WP_003076994.1 ABC transporter ATP-binding protein -
  SCIM_RS06095 (SCIM_1099) - 1253831..1255567 (-) 1737 WP_003076797.1 ABC transporter ATP-binding protein -
  SCIM_RS06100 (SCIM_1100) endA 1255721..1256566 (-) 846 WP_003076919.1 DNA/RNA non-specific endonuclease Machinery gene
  SCIM_RS06105 - 1256629..1256805 (-) 177 WP_003072163.1 DNA-directed RNA polymerase subunit beta -
  SCIM_RS06110 (SCIM_1101) murA 1256798..1258078 (-) 1281 WP_003072160.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SCIM_RS09715 (SCIM_1102) - 1258116..1258346 (-) 231 WP_014829739.1 DUF1146 family protein -
  SCIM_RS06115 (SCIM_1103) - 1258452..1259288 (-) 837 WP_003076412.1 class C sortase -
  SCIM_RS06120 (SCIM_1104) - 1259343..1260977 (-) 1635 WP_003076532.1 SpaA isopeptide-forming pilin-related protein -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30744.37 Da        Isoelectric Point: 10.3160

>NTDB_id=51876 SCIM_RS06100 WP_003076919.1 1255721..1256566(-) (endA) [Streptococcus intermedius JTH08]
MSQRKSNQKVMQSVIGGIIALSLAIGAYYFRTNNNGTVHQDSSAINKSLEQHHAGPSKDLAQSVLTGNVRSQFKGKIEWN
GAGAFIVNENKNDLDAKVGSIPYADNKTKLVRGRTVPTVANALLSKATRQYRNREETGNGSTTWTPAGWHQVKHLSGEYH
HAVDRGHLLGYALIGNLKGFDASTSNPKNIAVQTAWANQANASHSTGQNFYETKVRKALDKNKRVRYRVTLIYASEQDLV
PVGSHIEAKSSDGSLEINVFVPNVQTGIRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=51876 SCIM_RS06100 WP_003076919.1 1255721..1256566(-) (endA) [Streptococcus intermedius JTH08]
ATGTCGCAGAGAAAATCCAATCAAAAAGTAATGCAGAGTGTTATTGGAGGGATTATTGCACTTAGTTTAGCTATTGGTGC
TTATTATTTTCGAACAAATAATAATGGTACAGTTCATCAAGATAGTTCTGCCATTAACAAAAGTCTCGAGCAACATCATG
CGGGTCCTAGTAAAGATCTGGCTCAGAGTGTATTGACAGGTAATGTGCGTTCACAATTTAAAGGGAAAATCGAGTGGAAT
GGCGCAGGAGCTTTTATTGTCAATGAGAATAAAAATGATTTAGATGCTAAAGTGGGAAGTATTCCTTATGCGGATAATAA
GACAAAATTGGTCAGAGGTCGAACTGTTCCGACGGTAGCAAATGCTCTTTTGTCTAAAGCTACTCGTCAGTATAGGAATC
GTGAAGAAACAGGTAATGGTTCAACAACTTGGACACCTGCTGGCTGGCATCAGGTGAAGCATTTATCAGGTGAATATCAT
CATGCAGTTGACCGTGGACATCTGCTAGGCTATGCCTTGATTGGTAACTTGAAAGGTTTTGATGCTTCGACTAGCAATCC
TAAAAATATTGCGGTGCAAACGGCTTGGGCGAATCAAGCAAATGCTAGCCATTCTACAGGTCAAAATTTTTATGAAACGA
AAGTACGTAAAGCTCTTGATAAAAATAAACGAGTTCGGTATCGAGTAACCTTGATTTACGCAAGTGAGCAGGATTTAGTA
CCGGTTGGTTCACATATTGAAGCCAAGTCTAGCGACGGTAGTTTGGAAATAAATGTCTTTGTGCCAAACGTACAGACAGG
AATTCGATTAAATTATCAGACAGGAGAAGTGACGGTCACCAACTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(112-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68.613

97.509

0.669
  endA Streptococcus pneumoniae D39

68.613

97.509

0.669
  endA Streptococcus pneumoniae R6

68.613

97.509

0.669
  endA Streptococcus pneumoniae TIGR4

68.613

97.509

0.669

Multiple sequence alignment