Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   I6H74_RS00940 Genome accession   NZ_CP066069
Coordinates   186647..187588 (-) Length   313 a.a.
NCBI ID   WP_014611930.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 181647..192588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS00900 (I6H74_00900) - 181652..182848 (-) 1197 WP_015057203.1 acetate kinase -
  I6H74_RS00905 (I6H74_00905) comYH 182907..183860 (-) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  I6H74_RS00910 (I6H74_00910) comGG 183923..184246 (-) 324 WP_227985720.1 competence type IV pilus minor pilin ComGG -
  I6H74_RS00915 (I6H74_00915) comGF 184275..184715 (-) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF -
  I6H74_RS00920 (I6H74_00920) comGE 184696..184941 (-) 246 WP_003058569.1 competence type IV pilus minor pilin ComGE -
  I6H74_RS00925 (I6H74_00925) comGD 184949..185377 (-) 429 WP_046177415.1 competence type IV pilus minor pilin ComGD -
  I6H74_RS00930 (I6H74_00930) comYC 185352..185678 (-) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H74_RS00935 (I6H74_00935) comYB 185680..186711 (-) 1032 WP_015057201.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H74_RS00940 (I6H74_00940) comGA/cglA 186647..187588 (-) 942 WP_014611930.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H74_RS00945 (I6H74_00945) - 187669..188034 (-) 366 WP_003055257.1 DUF1033 family protein -
  I6H74_RS00950 (I6H74_00950) rpoC 188237..191878 (-) 3642 WP_046177414.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35165.29 Da        Isoelectric Point: 7.5610

>NTDB_id=517079 I6H74_RS00940 WP_014611930.1 186647..187588(-) (comGA/cglA) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MVQALARSILKEAEQIQAQDIYILPKENQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGGDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGHLSPEQARFEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=517079 I6H74_RS00940 WP_014611930.1 186647..187588(-) (comGA/cglA) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATTCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AAATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGGAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACATTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGCAAAACGACTTTGATGCACCAATTGATTGCTGATTATTATCAAGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGTAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.935

99.042

0.613
  comYA Streptococcus mutans UA140

61.415

99.361

0.61
  comYA Streptococcus mutans UA159

61.415

99.361

0.61
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.361

0.604
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.486

99.361

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

52.412

99.361

0.521
  comGA Latilactobacillus sakei subsp. sakei 23K

38.908

93.61

0.364