Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   I6H76_RS02385 Genome accession   NZ_CP065994
Coordinates   473904..474770 (-) Length   288 a.a.
NCBI ID   WP_006532342.1    Uniprot ID   A0A380KLV6
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 468904..479770
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS02370 (I6H76_02370) pheT 469537..471942 (-) 2406 WP_043878417.1 phenylalanine--tRNA ligase subunit beta -
  I6H76_RS02375 (I6H76_02375) - 472012..472536 (-) 525 WP_006532344.1 N-acetyltransferase -
  I6H76_RS02380 (I6H76_02380) pheS 472569..473612 (-) 1044 WP_043878396.1 phenylalanine--tRNA ligase subunit alpha -
  I6H76_RS02385 (I6H76_02385) endA 473904..474770 (-) 867 WP_006532342.1 DNA/RNA non-specific endonuclease Machinery gene
  I6H76_RS02390 (I6H76_02390) - 474875..475063 (-) 189 WP_006532341.1 DNA-directed RNA polymerase subunit beta -
  I6H76_RS02395 (I6H76_02395) murA 475067..476341 (-) 1275 WP_043878395.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  I6H76_RS02400 (I6H76_02400) - 476403..476639 (-) 237 WP_006532339.1 DUF1146 family protein -
  I6H76_RS02405 (I6H76_02405) - 476784..477200 (-) 417 WP_006532338.1 F0F1 ATP synthase subunit epsilon -
  I6H76_RS02410 (I6H76_02410) atpD 477213..478619 (-) 1407 WP_006532337.1 F0F1 ATP synthase subunit beta -
  I6H76_RS02415 (I6H76_02415) - 478684..479562 (-) 879 WP_006532336.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 30996.19 Da        Isoelectric Point: 8.2632

>NTDB_id=516108 I6H76_RS02385 WP_006532342.1 473904..474770(-) (endA) [Streptococcus infantarius strain FDAARGOS_1019]
MAKKSKLSKQTKSFISLLVLLVSIGAGWLTTSDSSDPVNQVISLITGESYSKIVSNQSSANQATPSQELAETVLTDNVKA
QLGSNLEWNGAGAYLVNGNKTDLNARVASKPYANNKTKIVQGQTIPTVANALLSKSTRQYRSREETGNGSTSWTPAGWHQ
VQNLSGTYSHAVDRGHLLGYALVGGLKGFDASTSNPENVATQTAWANEASSEDSTGQNYYEGQVRRALDQNKRVRYRVTL
IYDGDNILASGTHLEAKSSDGSLEFNVFIPNVQSGLSFDYYSGQVSVN

Nucleotide


Download         Length: 867 bp        

>NTDB_id=516108 I6H76_RS02385 WP_006532342.1 473904..474770(-) (endA) [Streptococcus infantarius strain FDAARGOS_1019]
ATGGCAAAGAAATCAAAACTGTCTAAACAGACAAAATCATTTATTTCTTTATTAGTTTTATTGGTTAGTATTGGTGCGGG
TTGGCTGACAACTTCAGATTCAAGTGATCCTGTTAATCAAGTTATTTCCTTGATTACGGGAGAATCATATTCAAAGATTG
TGTCAAATCAGTCTTCTGCTAATCAAGCAACACCAAGTCAAGAATTGGCTGAAACAGTTTTGACAGATAATGTTAAGGCT
CAGCTTGGTTCAAATTTAGAATGGAACGGTGCGGGAGCTTATTTGGTTAACGGAAATAAAACCGATTTGAATGCAAGAGT
AGCCAGTAAACCTTATGCCAATAACAAAACAAAAATTGTGCAAGGTCAGACTATTCCAACGGTCGCAAATGCTTTGTTGA
GTAAGTCGACACGTCAATATAGAAGCCGTGAGGAAACTGGAAATGGCTCAACTTCATGGACACCAGCGGGCTGGCACCAA
GTGCAAAATCTTTCTGGAACATACAGTCACGCCGTGGACCGTGGGCACTTGCTCGGCTATGCTTTAGTTGGTGGCTTAAA
AGGCTTTGATGCTTCAACAAGCAACCCTGAAAATGTAGCCACTCAGACAGCCTGGGCAAATGAAGCTAGTTCAGAAGACT
CAACGGGTCAAAATTACTACGAGGGTCAGGTCAGAAGAGCGCTTGATCAGAATAAACGTGTTCGTTACCGCGTGACCTTG
ATTTATGATGGCGATAATATTCTTGCTAGCGGGACACATTTGGAAGCAAAATCATCTGATGGTAGTTTAGAGTTTAATGT
TTTCATTCCGAATGTGCAAAGTGGTTTAAGCTTTGATTATTATTCAGGTCAGGTTAGTGTGAATTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(97-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A380KLV6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

69.068

81.944

0.566
  endA Streptococcus pneumoniae D39

69.068

81.944

0.566
  endA Streptococcus pneumoniae R6

69.068

81.944

0.566
  endA Streptococcus pneumoniae TIGR4

69.068

81.944

0.566