Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   KZH43_RS07005 Genome accession   NZ_CP079923
Coordinates   1414196..1414984 (-) Length   262 a.a.
NCBI ID   WP_000940734.1    Uniprot ID   Q8DP01
Organism   Streptococcus pneumoniae strain Rx1     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1409196..1419984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZH43_RS06975 (KZH43_06975) - 1410182..1410694 (-) 513 WP_001049323.1 adenine phosphoribosyltransferase -
  KZH43_RS06980 (KZH43_06980) - 1410782..1411540 (-) 759 WP_053039685.1 class I SAM-dependent methyltransferase -
  KZH43_RS06985 (KZH43_06985) - 1411748..1411894 (+) 147 WP_000403100.1 hypothetical protein -
  KZH43_RS06990 (KZH43_06990) - 1412041..1413171 (-) 1131 WP_000229961.1 ABC transporter ATP-binding protein -
  KZH43_RS07000 (KZH43_07000) - 1413621..1414196 (-) 576 WP_000158722.1 cysteine hydrolase family protein -
  KZH43_RS07005 (KZH43_07005) codY 1414196..1414984 (-) 789 WP_000940734.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  KZH43_RS07010 (KZH43_07010) - 1415248..1416822 (-) 1575 WP_000671113.1 DEAD/DEAH box helicase -
  KZH43_RS07015 (KZH43_07015) - 1417021..1418247 (-) 1227 WP_000841575.1 OFA family MFS transporter -
  KZH43_RS07020 (KZH43_07020) - 1418437..1419754 (+) 1318 Protein_1416 FAD-containing oxidoreductase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29756.11 Da        Isoelectric Point: 5.4646

>NTDB_id=515724 KZH43_RS07005 WP_000940734.1 1414196..1414984(-) (codY) [Streptococcus pneumoniae strain Rx1]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=515724 KZH43_RS07005 WP_000940734.1 1414196..1414984(-) (codY) [Streptococcus pneumoniae strain Rx1]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTCCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTGCCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGCAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DP01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.374

93.893

0.454