Detailed information NTG0514265

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STMM8_RS05320
• Genome accession: NZ_CP065787
• Coordinates: 1011535..1012416 (-)
• Length: 293 a.a.
• NCBI ID: WP_022096754.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MM8
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1006535..1017416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STMM8_RS05295 (STMM8_05325)	vicR	1007239..1007946 (-)	708	WP_011226084.1	response regulator YycF	Regulator
STMM8_RS05300 (STMM8_05330)	-	1008473..1009240 (+)	768	WP_022096757.1	amino acid ABC transporter ATP-binding protein	-
STMM8_RS05305 (STMM8_05335)	-	1009252..1010085 (+)	834	WP_022096756.1	transporter substrate-binding domain-containing protein	-
STMM8_RS05310 (STMM8_05340)	-	1010103..1010801 (+)	699	WP_022096755.1	amino acid ABC transporter permease	-
STMM8_RS05315 (STMM8_05345)	-	1010813..1011463 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
STMM8_RS05320 (STMM8_05350)	endA	1011535..1012416 (-)	882	WP_022096754.1	DNA/RNA non-specific endonuclease	Machinery gene
STMM8_RS05325 (STMM8_05355)	-	1012478..1012666 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STMM8_RS05330 (STMM8_05360)	murA	1012668..1013939 (-)	1272	WP_022096753.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STMM8_RS05335 (STMM8_05365)	-	1014009..1014245 (-)	237	WP_002946959.1	DUF1146 family protein	-
STMM8_RS05340 (STMM8_05370)	galE	1014433..1015446 (-)	1014	WP_002946961.1	UDP-glucose 4-epimerase GalE	-
STMM8_RS05345 (STMM8_05375)	-	1015406..1016077 (-)	672	WP_331251216.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31813.61 Da
• Isoelectric Point: 10.1789

>NTDB_id=514265 STMM8_RS05320 WP_022096754.1 1011535..1012416(-) (endA) [Streptococcus thermophilus strain MM8]
MAKRKTSLTNKQKRQLVTLIIAVLIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSINSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=514265 STMM8_RS05320 WP_022096754.1 1011535..1012416(-) (endA) [Streptococcus thermophilus strain MM8]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGTTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAATAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.635	86.007	0.608
endA	Streptococcus pneumoniae D39	70.635	86.007	0.608
endA	Streptococcus pneumoniae R6	70.635	86.007	0.608
endA	Streptococcus pneumoniae TIGR4	70.635	86.007	0.608