Detailed information NTG0511392

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: STCNRZ1202_RS07185
• Genome accession: NZ_CP065506
• Coordinates: 1377209..1377904 (-)
• Length: 231 a.a.
• NCBI ID: WP_347229590.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ1202
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1372209..1382904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1202_RS07170 (STCNRZ1202_07190)	-	1373020..1373565 (-)	546	WP_347229588.1	GNAT family N-acetyltransferase	-
STCNRZ1202_RS07175 (STCNRZ1202_07195)	-	1373631..1374893 (-)	1263	WP_022096991.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STCNRZ1202_RS07180 (STCNRZ1202_07200)	-	1374979..1377219 (-)	2241	WP_347229589.1	DNA internalization-related competence protein ComEC/Rec2	-
STCNRZ1202_RS07185 (STCNRZ1202_07205)	comEA	1377209..1377904 (-)	696	WP_347229590.1	helix-hairpin-helix domain-containing protein	Machinery gene
STCNRZ1202_RS07190 (STCNRZ1202_07210)	-	1378011..1378766 (-)	756	WP_347229591.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
STCNRZ1202_RS07195	-	1379255..1379493 (+)	239	Protein_1362	polysaccharide deacetylase family protein	-
STCNRZ1202_RS07200	-	1379542..1379820 (+)	279	WP_002948857.1	hypothetical protein	-
STCNRZ1202_RS07205 (STCNRZ1202_07220)	-	1379836..1381092 (-)	1257	Protein_1364	ISL3-like element ISSth1 family transposase	-
STCNRZ1202_RS07210 (STCNRZ1202_07225)	-	1381303..1382055 (+)	753	WP_002948852.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
STCNRZ1202_RS07215 (STCNRZ1202_07230)	-	1382072..1382341 (+)	270	WP_002948849.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 231 a.a.
• Molecular weight: 24513.47 Da
• Isoelectric Point: 4.7123

>NTDB_id=511392 STCNRZ1202_RS07185 WP_347229590.1 1377209..1377904(-) (comEA) [Streptococcus thermophilus strain CNRZ1202]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKNENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide

• Length: 696 bp

>NTDB_id=511392 STCNRZ1202_RS07185 WP_347229590.1 1377209..1377904(-) (comEA) [Streptococcus thermophilus strain CNRZ1202]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGTATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAAATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (85-138)

• Helix-hairpin-helix motif (HHH_3) (167-228)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	98.701	100	0.987
comEA/celA/cilE	Streptococcus mitis SK321	40.611	99.134	0.403
comEA/celA/cilE	Streptococcus pneumoniae D39	39.035	98.701	0.385
comEA/celA/cilE	Streptococcus pneumoniae R6	39.035	98.701	0.385
comEA/celA/cilE	Streptococcus pneumoniae Rx1	39.035	98.701	0.385
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	39.035	98.701	0.385
comEA/celA/cilE	Streptococcus mitis NCTC 12261	37.719	98.701	0.372