Detailed information NTG0511382

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STCNRZ1202_RS05310
• Genome accession: NZ_CP065506
• Coordinates: 1001442..1002323 (-)
• Length: 293 a.a.
• NCBI ID: WP_011226089.1
• Uniprot ID: Q5M441
• Organism: Streptococcus thermophilus strain CNRZ1202
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 996442..1007323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1202_RS05285 (STCNRZ1202_05320)	vicR	997142..997849 (-)	708	WP_011227274.1	response regulator YycF	Regulator
STCNRZ1202_RS05290 (STCNRZ1202_05325)	-	998381..999148 (+)	768	WP_011226085.1	amino acid ABC transporter ATP-binding protein	-
STCNRZ1202_RS05295 (STCNRZ1202_05330)	-	999160..999993 (+)	834	WP_347229540.1	transporter substrate-binding domain-containing protein	-
STCNRZ1202_RS05300 (STCNRZ1202_05335)	-	1000011..1000709 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
STCNRZ1202_RS05305 (STCNRZ1202_05340)	-	1000721..1001371 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
STCNRZ1202_RS05310 (STCNRZ1202_05345)	endA	1001442..1002323 (-)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
STCNRZ1202_RS05315 (STCNRZ1202_05350)	-	1002385..1002573 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STCNRZ1202_RS05320 (STCNRZ1202_05355)	murA	1002575..1003846 (-)	1272	WP_041828250.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STCNRZ1202_RS05325 (STCNRZ1202_05360)	-	1003916..1004152 (-)	237	WP_002946959.1	DUF1146 family protein	-
STCNRZ1202_RS05330 (STCNRZ1202_05365)	galE	1004340..1005353 (-)	1014	WP_096811494.1	UDP-glucose 4-epimerase GalE	-
STCNRZ1202_RS05335 (STCNRZ1202_05370)	-	1005368..1005802 (-)	435	WP_347229541.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31757.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=511382 STCNRZ1202_RS05310 WP_011226089.1 1001442..1002323(-) (endA) [Streptococcus thermophilus strain CNRZ1202]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=511382 STCNRZ1202_RS05310 WP_011226089.1 1001442..1002323(-) (endA) [Streptococcus thermophilus strain CNRZ1202]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

3D structure

• AlphaFold DB: Q5M441

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594