Detailed information NTG0511107

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: ST4067_RS09490
• Genome accession: NZ_CP065496
• Coordinates: 1819407..1820642 (+)
• Length: 411 a.a.
• NCBI ID: WP_014608809.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4067
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1814407..1825642

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4067_RS09460 (ST4067_09505)	-	1814872..1817478 (+)	2607	WP_263604550.1	YfhO family protein	-
ST4067_RS09480 (ST4067_09525)	-	1818023..1818706 (-)	684	WP_164178359.1	YoaK family protein	-
ST4067_RS09485 (ST4067_09530)	rlmH	1818722..1819201 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
ST4067_RS09490 (ST4067_09535)	htrA	1819407..1820642 (+)	1236	WP_014608809.1	S1C family serine protease	Regulator
ST4067_RS09495 (ST4067_09540)	spo0J	1820708..1821475 (+)	768	WP_011226714.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42915.25 Da
• Isoelectric Point: 4.7061

>NTDB_id=511107 ST4067_RS09490 WP_014608809.1 1819407..1820642(+) (htrA) [Streptococcus thermophilus strain 4067]
MKKFNWKKIVVPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTVKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=511107 ST4067_RS09490 WP_014608809.1 1819407..1820642(+) (htrA) [Streptococcus thermophilus strain 4067]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGTGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGTTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGAATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (6-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.097	100	0.601
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus mitis NCTC 12261	53.79	99.513	0.535
htrA	Streptococcus pneumoniae TIGR4	53.545	99.513	0.533
htrA	Streptococcus pneumoniae D39	53.545	99.513	0.533
htrA	Streptococcus pneumoniae Rx1	53.545	99.513	0.533
htrA	Streptococcus pneumoniae R6	53.545	99.513	0.533