Detailed information NTG0511082

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ST4067_RS05355
• Genome accession: NZ_CP065496
• Coordinates: 1012485..1013366 (-)
• Length: 293 a.a.
• NCBI ID: WP_002953146.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4067
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1007485..1018366

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4067_RS05330 (ST4067_05355)	vicR	1008173..1008880 (-)	708	WP_011227274.1	response regulator YycF	Regulator
ST4067_RS05335 (ST4067_05360)	-	1009424..1010191 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
ST4067_RS05340 (ST4067_05365)	-	1010203..1011036 (+)	834	WP_011226086.1	transporter substrate-binding domain-containing protein	-
ST4067_RS05345 (ST4067_05370)	-	1011054..1011752 (+)	699	WP_065973256.1	amino acid ABC transporter permease	-
ST4067_RS05350 (ST4067_05375)	-	1011764..1012414 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
ST4067_RS05355 (ST4067_05380)	endA	1012485..1013366 (-)	882	WP_002953146.1	DNA/RNA non-specific endonuclease	Machinery gene
ST4067_RS05360 (ST4067_05385)	-	1013428..1013616 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
ST4067_RS05365 (ST4067_05390)	murA	1013618..1014889 (-)	1272	WP_179970494.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ST4067_RS05370 (ST4067_05395)	-	1014959..1015195 (-)	237	WP_002946959.1	DUF1146 family protein	-
ST4067_RS05375 (ST4067_05400)	galE	1015383..1016396 (-)	1014	WP_011227279.1	UDP-glucose 4-epimerase GalE	-
ST4067_RS05380 (ST4067_05405)	-	1016411..1016845 (-)	435	WP_011227280.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.54 Da
• Isoelectric Point: 10.2316

>NTDB_id=511082 ST4067_RS05355 WP_002953146.1 1012485..1013366(-) (endA) [Streptococcus thermophilus strain 4067]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRKVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=511082 ST4067_RS05355 WP_002953146.1 1012485..1013366(-) (endA) [Streptococcus thermophilus strain 4067]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGAAAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594