Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   KU525_RS13410 Genome accession   NZ_CP077920
Coordinates   2722600..2723373 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain 277     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2717600..2728373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU525_RS13375 (KU525_13420) - 2717853..2718623 (-) 771 WP_000473699.1 isoprenyl transferase -
  KU525_RS13380 (KU525_13425) frr 2718996..2719550 (-) 555 WP_001280006.1 ribosome recycling factor -
  KU525_RS13385 (KU525_13430) pyrH 2719569..2720291 (-) 723 WP_000057330.1 UMP kinase -
  KU525_RS13390 (KU525_13435) tsf 2720428..2721309 (-) 882 WP_000201387.1 translation elongation factor Ts -
  KU525_RS13395 (KU525_13440) - 2721344..2721457 (-) 114 WP_001789890.1 hypothetical protein -
  KU525_RS13400 (KU525_13445) rpsB 2721491..2722258 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  KU525_RS13405 (KU525_13450) - 2722457..2722549 (-) 93 WP_031788481.1 hypothetical protein -
  KU525_RS13410 (KU525_13455) codY 2722600..2723373 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  KU525_RS13415 (KU525_13460) hslU 2723398..2724801 (-) 1404 WP_225806194.1 ATP-dependent protease ATPase subunit HslU -
  KU525_RS13420 (KU525_13465) hslV 2724867..2725412 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  KU525_RS13425 (KU525_13470) xerC 2725409..2726305 (-) 897 WP_001015597.1 tyrosine recombinase XerC -
  KU525_RS13430 (KU525_13475) trmFO 2726722..2728029 (-) 1308 WP_000195259.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=511072 KU525_RS13410 WP_000055337.1 2722600..2723373(-) (codY) [Staphylococcus aureus strain 277]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=511072 KU525_RS13410 WP_000055337.1 2722600..2723373(-) (codY) [Staphylococcus aureus strain 277]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATCCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTTCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428