Detailed information NTG0510963

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ST4021_RS05430
• Genome accession: NZ_CP065493
• Coordinates: 1044541..1045422 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4021
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1039541..1050422

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4021_RS05405 (ST4021_05450)	vicR	1040248..1040955 (-)	708	WP_011681206.1	response regulator YycF	Regulator
ST4021_RS05410 (ST4021_05455)	-	1041479..1042246 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
ST4021_RS05415 (ST4021_05460)	-	1042258..1043091 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
ST4021_RS05420 (ST4021_05465)	-	1043109..1043807 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
ST4021_RS05425 (ST4021_05470)	-	1043819..1044469 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
ST4021_RS05430 (ST4021_05475)	endA	1044541..1045422 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
ST4021_RS05435 (ST4021_05480)	-	1045484..1045672 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
ST4021_RS05440 (ST4021_05485)	murA	1045674..1046945 (-)	1272	WP_011681211.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ST4021_RS05445 (ST4021_05490)	-	1047015..1047251 (-)	237	WP_002946959.1	DUF1146 family protein	-
ST4021_RS05450 (ST4021_05495)	galE	1047439..1048452 (-)	1014	WP_011681212.1	UDP-glucose 4-epimerase GalE	-
ST4021_RS05455 (ST4021_05500)	-	1048467..1048970 (-)	504	WP_011681213.1	hypothetical protein	-
ST4021_RS05460 (ST4021_05505)	-	1048960..1049412 (-)	453	WP_011681214.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=510963 ST4021_RS05430 WP_011681210.1 1044541..1045422(-) (endA) [Streptococcus thermophilus strain 4021]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=510963 ST4021_RS05430 WP_011681210.1 1044541..1045422(-) (endA) [Streptococcus thermophilus strain 4021]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594