Detailed information NTG0510842

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STCNRZ887_RS05220
• Genome accession: NZ_CP065491
• Coordinates: 1005147..1006028 (-)
• Length: 293 a.a.
• NCBI ID: WP_011226089.1
• Uniprot ID: Q5M441
• Organism: Streptococcus thermophilus strain CNRZ887
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1000147..1011028

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ887_RS05195 (STCNRZ887_05230)	vicR	1000847..1001554 (-)	708	WP_011227274.1	response regulator YycF	Regulator
STCNRZ887_RS05200 (STCNRZ887_05235)	-	1002086..1002853 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
STCNRZ887_RS05205 (STCNRZ887_05240)	-	1002865..1003698 (+)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
STCNRZ887_RS05210 (STCNRZ887_05245)	-	1003716..1004414 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
STCNRZ887_RS05215 (STCNRZ887_05250)	-	1004426..1005076 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
STCNRZ887_RS05220 (STCNRZ887_05255)	endA	1005147..1006028 (-)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
STCNRZ887_RS05225 (STCNRZ887_05260)	-	1006090..1006278 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
STCNRZ887_RS05230 (STCNRZ887_05265)	murA	1006280..1007551 (-)	1272	WP_041828250.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STCNRZ887_RS05235 (STCNRZ887_05270)	-	1007621..1007857 (-)	237	WP_179971627.1	DUF1146 family protein	-
STCNRZ887_RS05240 (STCNRZ887_05275)	galE	1008045..1009058 (-)	1014	WP_011227279.1	UDP-glucose 4-epimerase GalE	-
STCNRZ887_RS05245 (STCNRZ887_05280)	-	1009073..1009528 (-)	456	WP_041827047.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31757.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=510842 STCNRZ887_RS05220 WP_011226089.1 1005147..1006028(-) (endA) [Streptococcus thermophilus strain CNRZ887]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=510842 STCNRZ887_RS05220 WP_011226089.1 1005147..1006028(-) (endA) [Streptococcus thermophilus strain CNRZ887]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCCCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

3D structure

• AlphaFold DB: Q5M441

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594