Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   SIR_RS11025 Genome accession   NC_022246
Coordinates   243109..245442 (+) Length   777 a.a.
NCBI ID   WP_021002397.1    Uniprot ID   T1ZDW1
Organism   Streptococcus intermedius B196     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 238109..250442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS11005 (SIR_0250) lepB 240605..241219 (-) 615 WP_020998280.1 signal peptidase I -
  SIR_RS11010 (SIR_0251) rnhC 241223..242113 (-) 891 WP_021002396.1 ribonuclease HIII -
  SIR_RS11015 - 242199..242504 (+) 306 WP_003074635.1 hypothetical protein -
  SIR_RS11020 (SIR_0252) - 242501..243049 (+) 549 WP_003070931.1 CvpA family protein -
  SIR_RS11025 (SIR_0253) mutS/mutS2 243109..245442 (+) 2334 WP_021002397.1 endonuclease MutS2 Machinery gene
  SIR_RS11030 (SIR_0254) - 245504..246925 (+) 1422 WP_021002398.1 C69 family dipeptidase -
  SIR_RS11035 (SIR_0255) trxA 247030..247344 (+) 315 WP_021002399.1 thioredoxin -
  SIR_RS11040 (SIR_0256) - 247506..248024 (-) 519 WP_021002400.1 DUF4865 family protein -
  SIR_RS11045 (SIR_0257) - 248133..248879 (+) 747 WP_021002401.1 LysR family transcriptional regulator -
  SIR_RS11050 (SIR_0258) - 248980..249387 (+) 408 WP_021002402.1 hypothetical protein -

Sequence

Protein


Download         Length: 777 a.a.        Molecular weight: 87796.44 Da        Isoelectric Point: 6.3128

>NTDB_id=51074 SIR_RS11025 WP_021002397.1 243109..245442(+) (mutS/mutS2) [Streptococcus intermedius B196]
MNRKILETLEFGKIKALFEPYLLTEQGRLELGQLFPSNKQERLETAFLEMTDMQQIFVQRPHFSLAATQDITGLTKRLEL
EGDLNIEEFLALKRILTVTQELTDFYDKLENVDLQRLNRLFEKLLAFPNLQGLLQAINEGGFVESFASDNLARIRRKIQE
NEVQVRDILQDILKTKGDMLVDQVVASRNGRNVLPVKNTFRNRISGVVHDISASGNTVYIEPRAVVNLNEEITNAQADER
HEILRILQELSDRIRPHIAEIANNAWIIGHLDLVRAKVCFIQERGAVVPMLSDSKDIRLLHVTHPLIENAVANDLYFASD
LTEIVITGPNTGGKTIMLKTLGLAQLMAQSGLPILADNGSRVGIFDQIFADIGDEQSIEQSLSTFSSHMTNIVAILEQVD
ENALVLLDELGAGTDPQEGAALAMAILEDLRLRQVKTMATTHYPELKAYGIEMAGVQNASMEFDTTSLRPTYRFMQGVPG
RSNALEIARRLGLSELVVRHAQEQTNTDSDVNRIIERLEEQTLESRKRLDNIREVEQENLKFNRALKKLYNEFNRERETE
LNKARLEAQEIVDLALSESESILKNLHDKSRLKPHEIIEAKAQLKKLAPETVDLSNNKVLKQAKKNRTPKVGDDILVTSY
GQRGTLVKQLKDGRWETQVGLIKMTLEEQEFNLLKAEKEQQPKRKQVNVVKRTTTSGPRARLDLRGKRYEEAMQELDAFI
DQALLNNMAQVDIIHGIGTGVIREGVTKYLRRNKHVKSFGYAPQNAGGSGATIVVFK

Nucleotide


Download         Length: 2334 bp        

>NTDB_id=51074 SIR_RS11025 WP_021002397.1 243109..245442(+) (mutS/mutS2) [Streptococcus intermedius B196]
ATGAATAGAAAAATTTTAGAAACATTAGAATTTGGGAAAATCAAGGCACTCTTTGAACCCTATCTGTTAACAGAACAAGG
CCGTTTAGAGCTAGGACAGCTTTTTCCATCTAATAAACAGGAACGGTTGGAGACAGCATTTTTAGAAATGACGGACATGC
AGCAGATTTTTGTGCAGCGTCCGCATTTCAGCTTGGCTGCGACTCAAGATATTACTGGACTGACCAAGCGTTTGGAGCTG
GAAGGCGACTTAAATATTGAAGAATTTCTTGCTCTGAAGCGTATTTTAACTGTCACGCAAGAATTAACTGATTTCTATGA
TAAGTTGGAAAATGTTGATTTGCAACGCTTGAACCGTCTTTTTGAAAAATTATTGGCTTTTCCTAACCTGCAAGGATTAC
TGCAAGCCATCAATGAGGGTGGATTTGTCGAAAGCTTTGCGAGTGACAATTTAGCTCGCATTCGTCGGAAAATTCAAGAA
AATGAAGTTCAAGTGAGAGATATTCTGCAAGATATTCTCAAAACGAAGGGCGATATGTTGGTAGATCAAGTAGTAGCCAG
TCGAAATGGTCGCAATGTTTTGCCAGTTAAAAATACATTTCGTAATCGGATTTCAGGCGTGGTACATGATATTTCTGCTA
GTGGAAATACAGTATATATCGAGCCGAGGGCAGTAGTCAACCTCAACGAAGAAATCACCAATGCACAGGCAGACGAGCGG
CATGAGATTCTACGTATCTTGCAAGAGTTGTCCGACCGAATACGTCCTCATATTGCTGAAATTGCTAATAACGCTTGGAT
TATTGGGCATTTGGATCTAGTTCGGGCAAAAGTGTGTTTTATACAGGAGAGAGGCGCGGTGGTGCCGATGCTGTCTGATA
GTAAGGATATTCGCCTGCTCCATGTTACTCATCCCTTGATAGAAAATGCAGTGGCTAATGATTTGTACTTTGCATCGGAT
TTAACGGAAATCGTCATTACTGGTCCTAACACAGGTGGGAAGACAATTATGCTGAAGACCTTGGGCTTGGCTCAGCTCAT
GGCGCAGTCTGGTCTGCCTATTTTGGCGGATAATGGTAGTCGAGTGGGGATTTTTGACCAAATTTTTGCCGACATCGGAG
ATGAGCAGTCTATTGAGCAGAGCTTATCGACTTTCTCTAGCCACATGACTAATATTGTTGCCATTTTAGAGCAAGTAGAC
GAAAATGCTCTGGTACTTCTGGATGAGCTTGGAGCTGGAACCGATCCGCAGGAGGGTGCAGCTCTTGCGATGGCAATCCT
TGAAGACCTGCGACTGCGGCAGGTCAAGACAATGGCAACGACTCATTACCCAGAGCTTAAGGCTTATGGGATTGAAATGG
CTGGCGTACAAAATGCTAGCATGGAGTTTGATACGACAAGTCTAAGACCAACTTATCGCTTTATGCAGGGGGTGCCAGGG
CGTTCTAATGCCCTTGAAATTGCTCGCCGTTTGGGCTTGTCGGAACTTGTCGTTCGCCATGCCCAAGAGCAGACCAACAC
GGACAGCGATGTCAATCGGATCATTGAGCGACTGGAGGAGCAAACGCTGGAAAGCCGCAAGCGCTTAGACAATATCCGTG
AGGTTGAGCAGGAAAATCTCAAATTTAACCGAGCACTCAAAAAACTTTACAATGAGTTTAACCGAGAGAGAGAAACCGAA
CTCAATAAGGCACGGTTGGAAGCTCAGGAAATCGTTGATTTGGCTTTGTCAGAGAGTGAGAGCATTCTCAAAAATCTCCA
TGATAAGTCTAGGCTCAAACCGCATGAGATTATCGAAGCTAAGGCCCAGCTTAAAAAGTTGGCGCCAGAAACCGTTGATT
TATCAAATAACAAGGTGCTCAAGCAGGCCAAGAAAAATCGTACGCCCAAGGTGGGAGATGATATTCTGGTGACCAGCTAT
GGTCAGCGGGGAACCTTGGTCAAGCAGCTCAAGGACGGCCGTTGGGAGACTCAGGTCGGTCTTATTAAGATGACTCTAGA
AGAGCAGGAATTTAATCTTCTAAAGGCTGAAAAGGAGCAGCAGCCTAAGCGCAAGCAGGTCAATGTGGTGAAACGAACAA
CCACAAGCGGGCCAAGGGCTAGACTGGATTTGCGAGGCAAGCGTTATGAAGAAGCTATGCAAGAGCTGGACGCCTTTATT
GATCAGGCTCTCCTCAACAACATGGCTCAGGTTGATATTATTCACGGTATCGGGACCGGTGTCATCCGCGAAGGGGTGAC
TAAGTACCTCCGCCGCAACAAGCACGTCAAGTCCTTTGGTTATGCTCCGCAAAATGCCGGTGGCAGCGGCGCGACGATTG
TGGTGTTTAAGTGA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(631-668)

Smr domain (Smr)

(702-777)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZDW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

38.91

100

0.395

Multiple sequence alignment