Detailed information NTG0510372

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: STCNRZ1151_RS05485
• Genome accession: NZ_CP065483
• Coordinates: 1027717..1028598 (-)
• Length: 293 a.a.
• NCBI ID: WP_011226089.1
• Uniprot ID: Q5M441
• Organism: Streptococcus thermophilus strain CNRZ1151
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1022717..1033598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1151_RS05460 (STCNRZ1151_05460)	vicR	1023417..1024124 (-)	708	WP_011227274.1	response regulator YycF	Regulator
STCNRZ1151_RS05465 (STCNRZ1151_05465)	-	1024656..1025423 (+)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
STCNRZ1151_RS05470 (STCNRZ1151_05470)	-	1025435..1026268 (+)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
STCNRZ1151_RS05475 (STCNRZ1151_05475)	-	1026286..1026984 (+)	699	WP_011226087.1	amino acid ABC transporter permease	-
STCNRZ1151_RS05480 (STCNRZ1151_05480)	-	1026996..1027646 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
STCNRZ1151_RS05485 (STCNRZ1151_05485)	endA	1027717..1028598 (-)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
STCNRZ1151_RS05490 (STCNRZ1151_05490)	-	1028660..1028848 (-)	189	WP_011227277.1	DNA-directed RNA polymerase subunit beta	-
STCNRZ1151_RS05495 (STCNRZ1151_05495)	murA	1028850..1030121 (-)	1272	WP_041827046.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STCNRZ1151_RS05500 (STCNRZ1151_05500)	-	1030191..1030427 (-)	237	WP_002946959.1	DUF1146 family protein	-
STCNRZ1151_RS05505 (STCNRZ1151_05505)	galE	1030615..1031628 (-)	1014	WP_011227279.1	UDP-glucose 4-epimerase GalE	-
STCNRZ1151_RS05510 (STCNRZ1151_05510)	-	1031643..1032098 (-)	456	WP_041827047.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31757.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=510372 STCNRZ1151_RS05485 WP_011226089.1 1027717..1028598(-) (endA) [Streptococcus thermophilus strain CNRZ1151]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVAGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=510372 STCNRZ1151_RS05485 WP_011226089.1 1027717..1028598(-) (endA) [Streptococcus thermophilus strain CNRZ1151]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTGCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCCCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

3D structure

• AlphaFold DB: Q5M441

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594