Detailed information NTG0510070

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ST4134_RS05495
• Genome accession: NZ_CP065478
• Coordinates: 1047273..1048154 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4134
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1042273..1053154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4134_RS05470 (ST4134_05465)	vicR	1042977..1043684 (-)	708	WP_011681206.1	response regulator YycF	Regulator
ST4134_RS05475 (ST4134_05470)	-	1044211..1044978 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
ST4134_RS05480 (ST4134_05475)	-	1044990..1045823 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
ST4134_RS05485 (ST4134_05480)	-	1045841..1046539 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
ST4134_RS05490 (ST4134_05485)	-	1046551..1047201 (+)	651	WP_024704148.1	amino acid ABC transporter permease	-
ST4134_RS05495 (ST4134_05490)	endA	1047273..1048154 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
ST4134_RS05500 (ST4134_05495)	-	1048216..1048404 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
ST4134_RS05505 (ST4134_05500)	murA	1048406..1049677 (-)	1272	WP_024704149.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ST4134_RS05510 (ST4134_05505)	-	1049747..1049983 (-)	237	WP_002946959.1	DUF1146 family protein	-
ST4134_RS05515 (ST4134_05510)	galE	1050172..1051185 (-)	1014	WP_014621668.1	UDP-glucose 4-epimerase GalE	-
ST4134_RS05520 (ST4134_05515)	-	1051200..1051634 (-)	435	WP_231107205.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=510070 ST4134_RS05495 WP_011681210.1 1047273..1048154(-) (endA) [Streptococcus thermophilus strain 4134]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=510070 ST4134_RS05495 WP_011681210.1 1047273..1048154(-) (endA) [Streptococcus thermophilus strain 4134]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594