Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   KU539_RS07205 Genome accession   NZ_CP077889
Coordinates   1488049..1490397 (+) Length   782 a.a.
NCBI ID   WP_001249285.1    Uniprot ID   Q2FHT7
Organism   Staphylococcus aureus strain 333     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1483049..1495397
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU539_RS07185 (KU539_07165) rnhC 1484158..1485096 (-) 939 WP_001284258.1 ribonuclease HIII -
  KU539_RS07190 (KU539_07170) zapA 1485466..1485725 (+) 260 Protein_1412 cell division protein ZapA -
  KU539_RS07195 (KU539_07175) - 1485733..1486254 (+) 522 WP_000234068.1 CvpA family protein -
  KU539_RS07200 (KU539_07180) polX 1486327..1488039 (+) 1713 WP_000161942.1 DNA polymerase/3'-5' exonuclease PolX -
  KU539_RS07205 (KU539_07185) mutS/mutS2 1488049..1490397 (+) 2349 WP_001249285.1 endonuclease MutS2 Machinery gene
  KU539_RS07210 (KU539_07190) trxA 1490570..1490884 (+) 315 WP_001018928.1 thioredoxin -
  KU539_RS07215 (KU539_07195) - 1490947..1491042 (-) 96 WP_001788625.1 hypothetical protein -
  KU539_RS07220 (KU539_07200) uvrC 1491208..1492989 (+) 1782 WP_000390529.1 excinuclease ABC subunit UvrC Machinery gene
  KU539_RS07225 (KU539_07205) - 1493313..1493927 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -

Sequence

Protein


Download         Length: 782 a.a.        Molecular weight: 88661.24 Da        Isoelectric Point: 6.1373

>NTDB_id=509940 KU539_RS07205 WP_001249285.1 1488049..1490397(+) (mutS/mutS2) [Staphylococcus aureus strain 333]
MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADI
GGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRS
KISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISR
LRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEDRTVYLPKAYHPLLNRETVVA
NTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNI
VEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTY
KLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQ
QFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIV
AGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIE
LDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK

Nucleotide


Download         Length: 2349 bp        

>NTDB_id=509940 KU539_RS07205 WP_001249285.1 1488049..1490397(+) (mutS/mutS2) [Staphylococcus aureus strain 333]
ATGAGACAAAAAACATTAGACGTCTTAGAATTTGAAAAAATAAAATCACTCGTTGCCAATGAAACTATTAGTGACTTAGG
CTTGGAAAAGGTCAATCAAATGATGCCAGCTACTAATTTTGAAACGGTTGTTTTTCAAATGGAAGAAACGGATGAGATTG
CTCAAATCTATAATAAGCATCGTTTACCAAGCTTGAGTGGCTTATCTAAAGTATCAGCATTCATTCATCGCGCTGATATT
GGCGGCGTTTTAAATGTATCAGAGCTTAACTTGATAAAAAGATTAATTCAAGTACAAAATCAATTCAAGACATTTTATAA
TCAATTGGTTGAAGAAGATGAAGGTGTTAAATACCCAATATTAGATGACAAGATGAATCAATTACCTGTGTTAACTGATC
TTTTTCAACAAATAAATGAAACATGCGATACGTATGATTTATATGATAATGCGAGTTATGAATTGCAAGGGATTAGAAGT
AAAATTTCTAGCACGAATCAACGTATTAGACAAAATTTGGACCGTATTGTTAAAAGCCAAGCAAATCAGAAAAAATTATC
AGATGCTATTGTAACAGTTAGGAATGAAAGAAACGTTATACCTGTCAAAGCTGAATATCGACAAGATTTTAATGGGATTG
TACATGATCAATCTGCTTCAGGACAAACATTGTATATTGAGCCATCATCAGTTGTTGAAATGAATAATCAAATTAGTCGA
TTACGTCATGACGAAGCAATTGAAAAAGAACGCATTTTAACGCAACTAACTGGTTATGTGGCTGCGGACAAAGATGCACT
ACTTGTGGCAGAACAAGTCATGGGTCAGTTAGATTTTTTAATCGCAAAAGCGAGATATAGTAGAAGTATTAAAGGAACAA
AGCCGATATTTAAAGAGGACCGTACTGTATATTTACCTAAAGCATACCATCCATTATTAAATCGTGAGACTGTTGTAGCT
AATACCATCGAATTTATGGAAGATATTGAAACGGTAATTATTACAGGACCGAATACAGGTGGTAAAACTGTAACATTAAA
AACATTAGGTTTAATTATTGTTATGGCTCAATCAGGATTGTTGATTCCCACACTTGATGGTAGTCAGTTAAGTGTATTTA
AAAATGTATATTGCGATATCGGAGATGAACAATCAATAGAACAATCATTATCAACTTTTTCATCTCATATGACGAATATA
GTTGAAATTTTAAAGCATGCAGACAAACATAGTTTAGTTTTATTTGATGAATTAGGTGCAGGTACAGATCCGAGTGAAGG
TGCTGCATTAGCAATGAGCATTTTAGATCATGTTAGAAAAATTGGTTCTCTAGTAATGGCAACGACGCACTATCCTGAAC
TTAAAGCATATAGTTATAATCGAGAAGGCGTTATGAATGCGAGTGTAGAATTTGATGTAGATACTTTGAGTCCAACGTAT
AAGTTATTAATGGGTGTGCCGGGTCGTTCAAATGCTTTTGACATTTCTAAAAAGTTAGGTCTTAGTTTGAATATTATTAA
TAAGGCTAAGACGATGATTGGTACTGATGAAAAAGAAATAAATGAAATGATTGAATCATTAGAGCGTAATTACAAACGTG
TAGAGACACAGAGGTTAGAACTGGACCGTCTTGTAAAAGAAGCGGAGCAAGTGCATGATGATTTATCTAAGCAGTATCAA
CAATTCCAAAATTATGAAAAGTCTCTAATAGAGGAAGCGAAAGAAAAAGCAAATCAGAAGATTAAGGCTGCAACAAAAGA
AGCTGACGATATTATTAAAGACTTAAGACAATTGCGTGAACAAAAAGGTGCAGATGTTAAAGAACATGAATTGATTGATA
AGAAGAAACGATTAGATGATCATTATGAAGCGAAATCTATAAAGCAAAATGTACAAAAGCAAAAATACGATAAAATTGTT
GCTGGTGATGAAGTAAAAGTATTATCTTACGGTCAAAAGGGTGAAGTTTTAGAAATTGTCAATGATGAAGAAGCAATTGT
TCAAATGGGAATTATTAAAATGAAGTTACCTATTGAAGATTTAGAGAAAAAACAAAAAGAAAAAGTTAAGCCAACGAAAA
TGGTTACACGTCAAAATCGTCAAACAATTAAAACTGAACTTGACTTACGAGGCTATCGTTATGAGGATGCTTTAATTGAA
CTAGATCAATATTTAGATCAAGCCGTTTTAAGTAATTACGAACAAGTTTATATCATTCATGGTAAAGGTACAGGTGCACT
TCAAAAAGGTGTACAACAACATTTGAAAAAGCATAAAAGTGTTAGTGACTTTAGAGGTGGTATGCCAAGCGAAGGTGGAT
TTGGCGTTACCGTTGCAACACTAAAATAA

Domains

Predicted by InterProScan.

MutS2 and Smr-associated SH3 domain (MSSS)

(641-681)

MutS domain V (MutS_V)

(332-512)

Smr domain (Smr)

(707-782)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2FHT7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

49.937

100

0.504