Detailed information NTG0509092

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ST1A_RS05475
• Genome accession: NZ_CP065384
• Coordinates: 1051746..1052627 (-)
• Length: 293 a.a.
• NCBI ID: WP_011681210.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 1A
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1046746..1057627

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST1A_RS05450 (ST1A_05430)	vicR	1047453..1048160 (-)	708	WP_011681206.1	response regulator YycF	Regulator
ST1A_RS05455 (ST1A_05435)	-	1048684..1049451 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
ST1A_RS05460 (ST1A_05440)	-	1049463..1050296 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
ST1A_RS05465 (ST1A_05445)	-	1050314..1051012 (+)	699	WP_011681209.1	amino acid ABC transporter permease	-
ST1A_RS05470 (ST1A_05450)	-	1051024..1051674 (+)	651	WP_011226088.1	amino acid ABC transporter permease	-
ST1A_RS05475 (ST1A_05455)	endA	1051746..1052627 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
ST1A_RS05480 (ST1A_05460)	-	1052689..1052877 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
ST1A_RS05485 (ST1A_05465)	murA	1052879..1054150 (-)	1272	WP_011681211.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ST1A_RS05490 (ST1A_05470)	-	1054220..1054456 (-)	237	WP_002946959.1	DUF1146 family protein	-
ST1A_RS05495 (ST1A_05475)	galE	1054644..1055657 (-)	1014	WP_347229818.1	UDP-glucose 4-epimerase GalE	-
ST1A_RS05500 (ST1A_05480)	-	1055672..1056175 (-)	504	WP_011681213.1	hypothetical protein	-
ST1A_RS05505 (ST1A_05485)	-	1056165..1056617 (-)	453	WP_011681214.1	hypothetical protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31773.50 Da
• Isoelectric Point: 10.1789

>NTDB_id=509092 ST1A_RS05475 WP_011681210.1 1051746..1052627(-) (endA) [Streptococcus thermophilus strain 1A]
MAKRKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLAETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=509092 ST1A_RS05475 WP_011681210.1 1051746..1052627(-) (endA) [Streptococcus thermophilus strain 1A]
ATGGCAAAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTGATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTGCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGATGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCCTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.803	81.57	0.594
endA	Streptococcus pneumoniae D39	72.803	81.57	0.594
endA	Streptococcus pneumoniae R6	72.803	81.57	0.594
endA	Streptococcus pneumoniae TIGR4	72.803	81.57	0.594