Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   KU524_RS01205 Genome accession   NZ_CP077863
Coordinates   276916..277689 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain 371     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 271916..282689
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU524_RS01170 (KU524_01165) - 272169..272939 (-) 771 WP_000473705.1 isoprenyl transferase -
  KU524_RS01175 (KU524_01170) frr 273312..273866 (-) 555 WP_001280006.1 ribosome recycling factor -
  KU524_RS01180 (KU524_01175) pyrH 273885..274607 (-) 723 WP_000057330.1 UMP kinase -
  KU524_RS01185 (KU524_01180) tsf 274744..275625 (-) 882 WP_000201386.1 translation elongation factor Ts -
  KU524_RS01190 (KU524_01185) - 275660..275773 (-) 114 WP_031845108.1 hypothetical protein -
  KU524_RS01195 (KU524_01190) rpsB 275807..276574 (-) 768 WP_000268484.1 30S ribosomal protein S2 -
  KU524_RS01200 (KU524_01195) - 276773..276865 (-) 93 WP_031788481.1 hypothetical protein -
  KU524_RS01205 (KU524_01200) codY 276916..277689 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  KU524_RS01210 (KU524_01205) hslU 277714..279117 (-) 1404 WP_047210673.1 ATP-dependent protease ATPase subunit HslU -
  KU524_RS01215 (KU524_01210) hslV 279183..279728 (-) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  KU524_RS01220 (KU524_01215) xerC 279725..280621 (-) 897 WP_001015609.1 tyrosine recombinase XerC -
  KU524_RS01225 (KU524_01220) trmFO 281039..282346 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=508934 KU524_RS01205 WP_000055337.1 276916..277689(-) (codY) [Staphylococcus aureus strain 371]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=508934 KU524_RS01205 WP_000055337.1 276916..277689(-) (codY) [Staphylococcus aureus strain 371]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428