Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   VB13_RS06875 Genome accession   NZ_CP077685
Coordinates   1380356..1381138 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain M49 591     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1375356..1386138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB13_RS06850 (VB13_07075) gatB 1375453..1376892 (-) 1440 WP_009880806.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  VB13_RS06855 (VB13_07080) gatA 1376892..1378358 (-) 1467 WP_011528911.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  VB13_RS06860 (VB13_07085) gatC 1378358..1378660 (-) 303 WP_012560907.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  VB13_RS06865 - 1378892..1379116 (-) 225 WP_237657501.1 putative PEP-binding protein -
  VB13_RS06870 (VB13_07090) - 1379655..1380209 (-) 555 WP_002983281.1 cysteine hydrolase family protein -
  VB13_RS06875 (VB13_07095) codY 1380356..1381138 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  VB13_RS06880 (VB13_07100) - 1381356..1382570 (-) 1215 WP_047235455.1 pyridoxal phosphate-dependent aminotransferase -
  VB13_RS06885 (VB13_07105) - 1382801..1383253 (+) 453 WP_002992571.1 universal stress protein -
  VB13_RS06890 (VB13_07110) - 1383376..1384764 (-) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  VB13_RS06895 (VB13_07115) - 1384836..1385801 (+) 966 WP_012560911.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=506892 VB13_RS06875 WP_002983278.1 1380356..1381138(-) (codY) [Streptococcus pyogenes strain M49 591]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=506892 VB13_RS06875 WP_002983278.1 1380356..1381138(-) (codY) [Streptococcus pyogenes strain M49 591]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504