Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   I2435_RS01645 Genome accession   NZ_CP065059
Coordinates   313072..313551 (+) Length   159 a.a.
NCBI ID   WP_111690409.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ25     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 308072..318551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2435_RS01645 (JFMEOBDD_00330) comX/sigX/comX2/sigX2 313072..313551 (+) 480 WP_111690409.1 competence protein ComX Regulator
  I2435_RS01650 (JFMEOBDD_00331) - 313696..314223 (+) 528 WP_012677393.1 YqeG family HAD IIIA-type phosphatase -
  I2435_RS01655 (JFMEOBDD_00332) yqeH 314223..315341 (+) 1119 WP_012677394.1 ribosome biogenesis GTPase YqeH -
  I2435_RS01660 (JFMEOBDD_00333) yhbY 315368..315676 (+) 309 WP_012516273.1 ribosome assembly RNA-binding protein YhbY -
  I2435_RS01665 (JFMEOBDD_00334) - 315760..316392 (+) 633 WP_012677395.1 nicotinate-nucleotide adenylyltransferase -
  I2435_RS01670 (JFMEOBDD_00335) yqeK 316389..316982 (+) 594 WP_012677396.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  I2435_RS01675 (JFMEOBDD_00336) rsfS 316984..317337 (+) 354 WP_012677397.1 ribosome silencing factor -
  I2435_RS01680 (JFMEOBDD_00337) - 317449..318210 (+) 762 WP_345771259.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19114.10 Da        Isoelectric Point: 7.3117

>NTDB_id=506473 I2435_RS01645 WP_111690409.1 313072..313551(+) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MSDDLVRLFDKIKPIIMKLRRHYYIQLWELDDWLQEGRLILYRLLVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQ
KRRFHKMAYEEIGAVGHAIPAGGLGVDDYVAYQLIVKEVEEQLTESELLQFRALIRGERFEGRRALLRKIGPYFQDFTG

Nucleotide


Download         Length: 480 bp        

>NTDB_id=506473 I2435_RS01645 WP_111690409.1 313072..313551(+) (comX/sigX/comX2/sigX2) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGAGTGATGATTTAGTGAGGTTGTTTGATAAGATCAAGCCTATTATTATGAAGCTAAGACGGCATTATTATATTCAGCT
GTGGGAGCTAGATGATTGGTTACAGGAGGGGCGGTTGATCTTGTATCGGTTATTGGTCACTTATCCAGAATTGATAGAGG
ATGAGGAGAAGCTGTACCGTTATTTTAAGACCAAGTTTTCCTCTTATTTGAAGGACGTGTTGCGGCAGCAGGAGAGTCAG
AAGCGTCGGTTTCATAAGATGGCTTATGAGGAGATTGGGGCGGTAGGGCATGCGATACCAGCAGGTGGCTTGGGAGTAGA
TGATTATGTGGCTTATCAGTTGATTGTGAAGGAGGTTGAGGAGCAATTGACAGAGAGCGAGCTGTTACAGTTTAGGGCTT
TGATCAGGGGAGAGCGGTTTGAGGGGAGACGGGCCTTGCTTCGCAAGATAGGACCTTACTTTCAGGACTTTACTGGCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

69.62

99.371

0.692
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

69.62

99.371

0.692
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

69.62

99.371

0.692
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

69.62

99.371

0.692
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

69.62

99.371

0.692
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

69.62

99.371

0.692
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.387

97.484

0.472
  comX/sigX Streptococcus mutans UA159

46.497

98.742

0.459
  comX Streptococcus sobrinus strain NIDR 6715-7

45.752

96.226

0.44
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

40.667

94.34

0.384
  comX Streptococcus thermophilus LMD-9

39.216

96.226

0.377
  comX Streptococcus thermophilus LMG 18311

39.216

96.226

0.377
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

39.735

94.969

0.377
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

39.735

94.969

0.377
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

39.333

94.34

0.371
  comX/comX2 Streptococcus pneumoniae Rx1

38.411

94.969

0.365
  comX/comX1 Streptococcus pneumoniae Rx1

38.411

94.969

0.365
  comX/comX2 Streptococcus pneumoniae D39

38.411

94.969

0.365
  comX/comX2 Streptococcus pneumoniae R6

38.411

94.969

0.365
  comX/comX1 Streptococcus pneumoniae R6

38.411

94.969

0.365
  comX/comX1 Streptococcus pneumoniae D39

38.411

94.969

0.365
  comX/comX2 Streptococcus pneumoniae TIGR4

38.411

94.969

0.365
  comX/comX1 Streptococcus pneumoniae TIGR4

38.411

94.969

0.365
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

38.667

94.34

0.365